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Stories tagged 'broadly neutralizing antibodies'

New library of HIV mutants could inform vaccine design

Laboratory manipulation of the AIDS-causing virus reveals evolutionary ‘dead-ends’

June 1, 2017 | By Rachel Tompa / Fred Hutch News Service

Fred Hutch researchers have created a library containing millions of mutant HIV viruses. Some of these mutants are very good at infecting human cells, no different from their “natural” viral ancestor. Some of them are worse. Together, they can teach researchers something important about HIV in humans.

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Empowering ‘millions of women’ against HIV

AMP study in sub-Saharan Africa tests an antibody infusion that could put protection in women’s hands

Oct. 21, 2016 | By Mary Engel / Fred Hutch News Service

The AMP study in sub-Saharan Africa will test whether an antibody infusion protects women against HIV. If it does, the finding will have particular significance for an epidemic that hits women on that continent especially hard and for which they have few prevention options.

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A new path to an AIDS vaccine?

A ‘landmark’ clinical trial called the AMP study launches on three continents to test HIV-blocking super antibodies

April 7, 2016 | By Mary Engel / Fred Hutch News Service

“It’s not often that you know that you’re starting a landmark study," says Dr. Larry Corey, founder and director of the HIV Vaccine Trials Network. Two of the world’s top HIV prevention clinical trial networks have joined forces to test an experimental antibody that could potentially protect people from infection by almost all strains of the rapidly mutating AIDS virus.

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