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Hutch News

Stories tagged 'blood-based proteins'

Researchers closer to early lung cancer detection

Sam Hanash leads discovery of blood proteins associated with early development of lung cancer; findings hold promise of a blood test for screening, diagnosis

Sept. 19, 2011 | By Kristen Woodward

A Fred Hutchinson Cancer Research Center team has discovered proteins in the blood that are associated with early lung cancer development in mice and humans. The advance brings the reality of a blood test for the early detection and diagnosis of lung cancer a step closer.

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Paulovich co-leads proteomics research center

Hutchinson Center and Broad Institute team will receive $9 million from NCI to search for protein biomarkers of cancer

Aug. 29, 2011 | By Kristen Woodward

The National Cancer Institute last week announced that a team co-led by Fred Hutchinson Cancer Research Center and the Broad Institute in Cambridge, Mass., has been selected to participate in the Clinical Proteomic Tumor Analysis Consortium, or CPTAC.

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Improving biomarker development to improve patient outcomes

Amanda Paulovich and colleagues find proof-of-concept study of biomarker development provides roadmap for similar approach in humans

June 20, 2011 | By Kristen Woodward

Fred Hutchinson Cancer Research Center researchers have demonstrated in mice that the performance of a novel biomarker-development pipeline using targeted mass spectrometry is robust enough to support the use of an analogous approach in humans. The findings, by principal investigator Dr. Amanda Paulovich of the Clinical Research Division, were published online June 19 in Nature Biotechnology.

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Biomarkers found for postmenopausal cardiovascular disease

WHI blood samples reveal new risk markers for heart disease, stroke

Aug. 2, 2010

Analysis by Fred Hutchinson Cancer Research Center scientists of blood protein data from the study participants in the Women's Health Initiative has revealed new biomarkers for stroke and coronary heart disease.

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Protein biomarker may aid earlier breast cancer detection

Li finds protein level rises months before diagnosis

May 3, 2010

According to findings by Fred Hutchinson Cancer Research Center researchers, levels of a protein implicated in several cancers—epidermal growth factor receptor—may be elevated in the blood of women up to 17 months prior to their breast cancer diagnosis.

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Proteins may predict breast-cancer survival

Markers for inflammation discovered in breast-cancer survivors are linked to survival

June 1, 2009 | By Dean Forbes

Fred Hutchinson Cancer Research Center-led research has identified two proteins in the blood that could become important prognostic markers for long-term survival in breast-cancer patients. The proteins are associated with chronic inflammation, which is known to contribute to cancer development and progression.

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