CRISPR gene-editing used on antibody-making B cells
May 17, 2019
| By Sabin Russell / Fred Hutch News Service
A Hutch team led by Dr. Justin Taylor shows that B cells, which are crucial components of the immune system, can be genetically engineered to make exactly the antibodies we want. It could lead to a potentially more precise and dependable way to generate protection without vaccines.
New approach, not yet tested in humans, aims to restore immune-powering B cells in cancer patients following successful CAR T-cell therapy
Oct. 17, 2016
| By Bill Briggs / Fred Hutch News Service
Scientists at Fred Hutch, Seattle Children’s Research Institute, and Technical University of Munich showed that activating a “kill switch” can turn off CAR T cells after doctors deem a cancer defeated, allowing normal B cells to again flourish.
Applicants wanted for most inclusive fellowship program among top cancer centers; Dr. Oliver Press honored as new Giuliani/Press Endowed Chair; possible new path to targeted therapies for certain leukemias, myelodysplastic syndrome.
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