New approach, not yet tested in humans, aims to restore immune-powering B cells in cancer patients following successful CAR T-cell therapy
Oct. 17, 2016
| By Bill Briggs / Fred Hutch News Service
Scientists at Fred Hutch, Seattle Children’s Research Institute, and Technical University of Munich showed that activating a “kill switch” can turn off CAR T cells after doctors deem a cancer defeated, allowing normal B cells to again flourish.
Study compares ‘alternative’ donor source vs. traditional transplantation of blood stem cells from an adult, unrelated donor
Sept. 7, 2016
| By Rachel Tompa / Fred Hutch News Service
A new study by Fred Hutch researchers, published today in The New England Journal of Medicine, has found that umbilical cord blood transplants may have advantages beyond being an alternative source of stem cells for patients without a traditional donor match. They also are associated with a lower risk of relapse in high-risk leukemia patients.