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Stories tagged 'Malaria'

On the path to a new-generation malaria vaccine

New approach using genetically modified parasite ‘primes the immune system’ in first human trial

Jan. 4, 2017 | By Mary Engel / Fred Hutch News Service

Volunteers in a clinical trial led by Fred Hutch's Dr. Jim Kublin endured 150 to 200 mosquito bites in one 10-minute session to test a new approach to a malaria vaccine that uses genetically attenuated, or weakened, parasites to stimulate an immune response to malaria without causing disease.

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Getting malaria on purpose

Volunteers roll up their sleeves and get infected to test an experimental drug

April 25, 2016 | By Mary Engel / Fred Hutch News Service

Eight healthy adults ranging in age from 20 to 37 are taking part in a new study conducted by the Seattle Malaria Clinical Trials Center, run by Fred Hutchinson Cancer Research Center and the Center for Infectious Disease Research.

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Malaria vaccine’s protectiveness depends on genetics of parasite

Genomics study, analysis help explain partial effectiveness, offer insights for improvement

Oct. 21, 2015 | By Mary Engel / Fred Hutch News Service

An experimental vaccine set to to win WHO approval as the first to even partially protect children against malaria works better against one strain of the disease-causing parasite than others.

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Finding a better way to take a bite out of malaria’s power

Fred Hutch and collaborators launch new trials to infect – and quickly treat – volunteers to test experimental drugs

Sept. 10, 2014 | By Mary Engel / Fred Hutch News Service

Fred Hutch and collaborators launch new trials to infect – and quickly treat – volunteers to test experimental drugs.

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Shredding the X chromosome: Wiping out female malaria-bearing mosquitos could halt disease

Scientists genetically modify mosquito responsible for spreading malaria so bugs produce mostly male offspring

June 27, 2014 | By Dr. Rachel Tompa

Scientists from Imperial College London and Fred Hutchinson Cancer Research Center have genetically modified the mosquito responsible for spreading malaria so the bugs produce mostly male offspring, a strategy that could eliminate the insect responsible for Africa's malaria plague.

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