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Stories tagged 'Clinical Research'

Tinkering with T cells

How researchers are tweaking engineered immune cells’ cancer-targeting receptors — and why it matters

May 15, 2018 | By Susan Keown / Fred Hutch News Service

These immune cells are the cornerstone of emerging cancer therapies. And their unimaginably tiny, cancer-targeting molecular weapons — their receptors — are the focus of intense scientific tinkering.

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Functional genomics provides a window into cancer's Achilles heels

Technique pinpoints unique tumor vulnerabilities — even when they are not written in tumor DNA

May 10, 2018 | By Sabrina Richards / Fred Hutch News Service

New findings by Dr. Christopher Kemp and colleagues demonstrate how functional genomics can highlight potential drug targets in patients with head and neck cancer.

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What's new in prostate cancer: 5 takeaways

‘Many reasons for optimism’ says expert at annual community symposium

May 1, 2018 | by Susan Keown / Fred Hutch News Service

What's new in prostate cancer in 2018? The latest in prostate cancer treatment, screening, survivorship and more.

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Gene editing holds promise for shrinking HIV ‘reservoir’

Study mimicking Timothy Ray Brown’s HIV-resistant mutation led to fewer latently infected cells — a key step toward driving the virus into remission without the need for antivirals

April 25, 2018 | By Mary Engel / Fred Hutch News Service

Fred Hutch study shows gene editing holds promise for shrinking HIV "reservoir" — a key step toward driving the virus into remission without the need for antivirals.

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‘Article of the Year’ nod to demo of machine learning for personalized medicine

Computer-generated algorithms could guide prevention, treatment of transplant complication, researchers showed

April 17, 2018 | By Susan Keown / Fred Hutch News Service

In its April issue, the American Journal of Epidemiology recognized a paper by Fred Hutchinson Cancer Research Center faculty member Dr. Elizabeth Krakow as one of its 10 best articles published in 2017.

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Immunotherapy strategy for ovarian cancer aims to rewire a ‘kill switch’ to ramp-up signal

T cells bearing a new engineered protein boost immunotherapy’s effectiveness in laboratory models of AML, ovarian, pancreatic cancers

April 16, 2018 | By Rachel Tompa / Fred Hutch News Service

In an effort to improve the efficacy of immunotherapy for solid tumors, Fred Hutch researchers have engineered a new type of protein that can rewire a 'kill switch' to stimulate T cells' activity instead.

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