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Stories tagged 'Basic Sciences'

Dr. Arvind Subramaniam receives grant to study how cells cope with stalled protein synthesis

National Science Foundation CAREER Award will enable him to develop computational models of this fundamental biological process

Jan. 30, 2019 | By Sabrina Richards / Fred Hutch News Service

Dr. Arvind “Rasi” Subramaniam has received a CAREER Award from the NSF to develop computational models of how cells cope with stalled protein synthesis.

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Cutting-edge approach maps HIV's escape routes

Atlas of immune-evading HIV mutations could inform design of new treatments, vaccines

Jan. 29, 2019 | By Sabrina Richards / Fred Hutch News Service

Fred Hutch scientists have constructed an atlas of mutations that HIV uses to escape broadly neutralizing antibodies, potent immune molecules that form our body’s first line of defense against the virus. The information could help guide researchers who are testing these antibodies’ potential to prevent or treat HIV infection, as well as those working to develop more effective preventive vaccines.

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For cells, keeping quiet is a cinch

Researchers show how dormant cells turn genes off by pulling DNA into loops

Jan. 3, 2019 | By Sabrina Richards / Fred Hutch News Service

Fred Hutch scientists discover that yeast cells use a specific protein to pull DNA into loops and help shut genes off as they enter a paused, energy-conserving state called quiescence.

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