Vaccine and Infectious Disease Division
Nearly one-quarter of cancers worldwide are caused by infectious diseases. Pathogens, such as Human Herpesvirus 8 (HHV-8) and Epstein Barr Virus (EBV), have been identified as contributing factors in lymphoma, sarcoma, liver cancer, prostate cancer, bladder cancer and stomach cancer. Researchers hope to answer a number of key questions: How are cancer-causing infections transmitted and acquired? What factors govern the progression from chronic infection to cancer? Which therapies can be employed to prevent infection-related cancers? VIDD has recently fostered a pioneering collaboration with the Uganda Cancer Institute, the only cancer care facility in Uganda, to delineate and establish efficacious treatment options.
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Research focus is HIV and herpesvirus vaccine development, herpes simplex virus type 2 (HSV-2) pathogenesis and the host immune response. Immunotherapeutic approaches to viral infections and cancer
Phone: (206) 667-6770
Fax: (206) 667-7711
Immune monitoring and correlative science analyses for early clinical trials in the area of cancer immunotherapy.
Determining how changes in microbial communities impact human health; identifying, characterizing, and culturing microbes found in the human genital tract; and associating the reproductive tract microbiome with human disease.
Developing molecular diagnostic tests to detect and identify pathogens in immunocompromised hosts such as cancer patients.
Phone: (206) 667-1935
Fax: (206) 667-4411
Immunologic endpoint determination for experimental vaccines (HIV, pneumococcus, malaria, TB, flu) and
Logistics, operations, quality assurance, and assay validation for immunologic evaluation of vaccines in the clinical trial setting
Study T cell fate and function in healthy and inflamed tissues and following infection with HIV and manipulate these responses for therapeutic purposes
Phone: (206) 667-2216
Fax: (206) 667-2209
Research focus includes HIV clinical trial design and conduct; complications of antiretroviral therapy and HIV-associated malignancies
Executive Director, China
Research is focused on longitudinal data analysis, survival time models, cancer prevention and screening trials, HIV vaccine evaluation; design, coordination, and analysis of clinical trial programs to evaluate promising candidate vaccines for globally important infectious diseases; analyses of immune response and viral genomic data to improve partly-efficacious vaccines
Phone: (206) 667-4944
Fax: (206) 667-4378
Epidemiology, natural history, therapy, and prevention of HSV and other herpesvirus infections; interactions between HSV and HIV Vaccines and clinical trials
Phone: (206) 520-4340
Primary responsibility is to facilitate and provide a platform for Hutch faculty to conduct their research, expand their research interests and translate their knowledge globally, particular in China
Phone: (206) 667-1937