Biostatistics

Vaccine and Infectious Disease Division

Biostatistics

The faculty who specialize in biostatistics research aim to: 1) conduct research in statistical methodology for the design and analysis of clinical, epidemiological and basic science studies; and 2) conduct research into biologically based mathematical models for pathogenesis. SCHARP, the Statistical Center for HIV/AIDS Research and Prevention, is a program housed within VIDD that provides services such as data collection, analysis and clinical trial management to collaborators worldwide. This program’s unique services have had far-reaching impacts on a number of HIV vaccine development trials and have played an integral role in these ground-breaking studies.

Faculty

Alphabetical Listing:

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Research Professor, Biostatistics, University of Washington
Graduate Faculty, Biostatistics, University of Washington
PI, Statistical and Data Management Center, Microbicide Trials Network
Design and analysis of trials for HIV prevention, joint models for longitudinal and survival data and statistical methods in HIV/AIDS and cardiovascular research.
Phone: (206) 667-1731
Fax: (206) 667-4812
Staff Scientist, Schiffer Group, Vaccine and Infectious Disease Division
Mathematical modeling of virus and immune system dynamics. Population/within-host dynamics approach to quantify HIV-1 infection and treatment efficacy (ordinary differential equations, nonlinear mixed effects models).
Phone: (206) 667-7940
Affiliate Professor, Biostatistics, University of Washington
Research focus includes the development of statistical methods for analysis of survival and longitudinal data from clinical trials and epidemiological studies.
Phone: (206) 667-7051
Fax: (206) 667-4378
Correlates analysis, sieve analysis and antigenic mapping focusing on HIV-1 vaccines and immunology
Phone: (206) 667-2569
Fax: (206) 667-4378
Senior Staff Scientist, Public Health Sciences Division
Affiliate Assistant Professor, Applied Mathematics, University of Washington
Research interests include mathematical modeling of infectious diseases, evaluating impact of interventions for HIV prevention, mathematical biology (population dynamics, epidemic modeling) and dynamical systems (ODE, PDE, and impulsive systems)
Research focus include clinical trial design; clinical trials data management in international settings, group and cluster randomized; analysis of sexual risk; and mediator analysis
Phone: (206) 667-5661
Fax: (206) 667-4378
Affiliate Assistant Professor, Biostatistics, University of Washington
Statistical and computational methods for bioinformatics applications, statistical modeling for genome sequence analysis and statistical modeling frameworks. The interface between computer science, statistics, and molecular biologyand such as development of new informatics methods in genomics and post-genomics
Phone: (206) 667-4086
Fax: (206) 667-4378
Associate Director, HPTN Statistical and Data Management Center, Vaccine and Infectious Disease Division
Clinical trial design and operations, good clinical data management practices (GCDMP), research regulations, behavioral research methodology, research ethics
Computational and statistical methods development for high-throughput, high-content biological data. Modeling and integration of data from high throughput assays for biomarker discovery, clinical outcome prediction and disease classification.
Phone: (206) 667-3116
Fax: (206) 667-4378
Current studies include development of methods for T-cell based sieve analysis, quantification of vaccine induced T cell responses, systems biology of influenza and time-dependent correlates analysis of HIV efficacy trial.
HVTN cross-protocol analyses
Affiliate Associate Professor, Biostatistics, University of Washington
Principal Investigator, Fong Group
Statistical problems in biological assays, Biological sequence analysis, Stochastic optimization
Phone: (206) 667-1093
Fax: (206) 667-4378
Principal Investigator, Statistical Data Management Center, HIV Vaccine Trials Network
Research Professor, Biostatistics, University of Washington
Graduate Faculty, Biostatistics, University of Washington
Research focus includes vaccine clinical trials, the design and analysis of Phase I/II trials, for evaluating vaccine effects on immune responses; the design and analysis of Phase 2b/III trials, for evaluating vaccine efficacy, immune correlates, sieve analysis, and post-infection vaccine effects; general biostatistical methods research, such as survival analysis, causal inference, and evaluation of surrogate endpoints
Phone: (206) 667-7299
Fax: (206) 667-4812
Affiliate Associate Professor, Statistics, University of Washington
Developing methods and tools for high throughput, high dimensional experiments with applications in vaccine research and immunology; flow cytometry, peptide microarrays, next generation sequencing; Bayesian inference and computation and statistical computing
Phone: (206) 667-4076
Fax: (206) 667-4378
Principal Staff Scientist, Vaccine and Infectious Disease Division
Assistant Clinical Professor, Biostatistics, Yale University, School of Public Health
Design, conduct, monitoring, and analysis of multicenter randomized clinical trials and comparative effectiveness studies, measuring and improving the effectiveness of informed consent in clinical research; improving the quality and efficiency of clinical trial data management; clinical research trials for the prevention or treatment of HIV / AIDS and vaccine clinical trials
Phone: (206) 667-6761
Fax: (206) 667-7767
Professor, Biostatistics, University of Washington
Adjunct Professor, Applied Mathematics and Epidemiology, University of Washington
Director and Founder, Summer Institute in Statistics and Modeling in Infectious Diseases, University of Washington
Research focus included the design and evaluation of vaccine field trials; modeling infectious disease dynamics and strategies for mitigation and control; causal inference in infectious diseases; and evaluating surrogates of protection.
Phone: (206) 667-2722
Fax: (206) 667-4378
Design and analytic methods for HIV prevention trials and measurement-error modeling and bias correction
Affiliate Associate Professor, Biostatistics, University of Washington
Statistical methods in biomarker evaluation for disease screening, surrogate endpoint identification, and treatment selection; genome-wide association studies and causal inference
Phone: (206) 667-4198
Fax: (206) 667-4378
Principal Staff Scientist, Vaccine and Infectious Disease Division
Principal Staff Scientist, Public Health Sciences Division
Unit Head, Biostatistical Collaborative Unit for Study Design and Data Analysis, Vaccine Immunology Statistical Center
Research focus include the design and analysis of clinical trials
Phone: (206) 667-5780
Fax: (206) 667-4378
Research focus includes statistical methods for bioassays (e.g., flow cytometry, sequencing); dynamic modeling of biological systems (e.g., multi-type cell populations, B-cell repertoire); nonparametric methods for supervised and unsupervised learning; stochastic processes (e.g., branching processes); algorithms for scalable data analysis.
Phone: (206) 667-2809
Fax: (206) 667-4378
Affiliate Associate Professor, Biostatistics, University of Washington
Graduate Faculty, Biostatistics, University of Washington
Clinical trials methodology; Vaccine evaluation; biomarker that predict an individual’s response to a given treatment and statistical analyses of vaccine trial data
Phone: (206) 667-6353
Fax: (206) 667-4378
Design and analysis of vaccine efficacy trials, genotype-specific vaccine efficacy-based sieve analysis,immune correlates of vaccine protection, analysis of vaccine-induced immune response durability and survival analysis
Phone: (206) 667-5568
Senior Staff Scientist, Public Health Sciences Division
Development of genetic statistical methodologies, including phylogenetic tree reconstruction from genetic sequences
Causal inference, semi/nonparametric methods, precision medicine, efficient estimation, machine learning, longitudinal data
Phone: (206) 667-4218
Research Associate Professor, Laboratory Medicine, University of Washington
Graduate Faculty, Laboratory Medicine, University of Washington
Statistical support to clinical research on HSV1 and HSV2 and other herpesvirus infections; Clinical association between herpes and HIV; statistical methods work in areas such as misclassification in time-to-event outcomes, laboratory assay validation, and methods for quantifying and examining risk factors for viral shedding
Phone: (206) 520-4316
Fax: (206) 520-4371
Research interests include analysis of immune response to vaccine candidates, study design for pilot studies, statistical methods for biological assays, and infectious disease models.
Phone: (206) 667-2310
Senior Staff Scientist, Public Health Sciences Division
Research focus includes vaccine clinical trials, SNP analysis, novel statistical methodology, nonparametric methods
Phone: (206) 667-7077
Fax: (206) 667-4378
Research Professor, Biostatistics, University of Washington
Adjunct Research Professor, Global Health, University of Washington
Graduate Faculty, Biostatistics and Global Health, University of Washington
Statistical methods for analyzing infectious disease data; developing methods to analyze infectious disease data and developing methods to analyze data with missing values
Phone: (206) 667-7788
Fax: (206) 667-4378
Associate Member, Clinical Research Division
Associate Professor, Department of Medicine, University of Washington
Attending Physician, SCCA Infectious Consulting Service, Seattle Cancer Care Alliance
Interest in describing the quantitative and dynamical features of human pathogens and immune responses. Most of work to-date is on the pathogenesis of HSV-2 infection but also interested in applying models to optimize viral eradication startegies, and to use models to capture kinetic features of the human microbiome.
Staff Scientist, Biostatistics, Bioinformatics & Epidemiology, Vaccine and Infectious Disease Division
Research interests include the design and analysis of group-sequential and complex clinical trials, specifically as pertaining to HIV prevention trials.
Phone: (206) 667-1186
Epidemiologic studies of infectious disease transmission, vaccine studies and the development of novel statistical methods and designs for studies of infectious disease transmission. Efficacy and effectiveness assessments of control and prevention strategies for infectious diseases of import to global health, including influenza, cholera, dengue, and tuberculosis
Research is focused on statistical analysis of survey data, Bayesian modeling including Bayesian nonparametrics and the design and analysis of vaccine studies
Research focus included statistical methods in HIV/AIDS research, diagnostic testing in medical research and clinical trials
Statistical methods in HIV/AIDS research and monitoring and analyzing drug adherence patterns. Transmission models for infectious disease epidemiology.
Phone: (206) 667-4526