Vaccine and Infectious Disease Division

Biomarkers

Early detection of certain diseases, such as cervical cancer or HIV, is a fundamental strategy for decreasing disease risk. VIDD researchers have shown that identification of clinically relevant biomarkers for detection in combination with early treatment can significantly improve patient survival rates. Biomarkers can also be used to optimize treatment strategies, ensuring each patient is given the treatment most likely to be effective and that unnecessary and ineffective treatment is avoided. Wide-ranging faculty research interests include statistical analyses of clinical trials; identification and evaluation of biomarkers for disease diagnosis, risk, and treatment efficacy; and genetic analysis of disease associations or effects.

Faculty

Research Professor, Biostatistics, University of Washington
Graduate Faculty, Biostatistics, University of Washington
PI, Statistical and Data Management Center, Microbicide Trials Network
Design and analysis of trials for HIV prevention, joint models for longitudinal and survival data and statistical methods in HIV/AIDS and cardiovascular research.
Phone: (206) 667-1731
Fax: (206) 667-4812
Affiliate Assistant Professor, Biostatistics, University of Washington
Research focus: Statistical methods in HIV prevention trials and in genetic association studies.
Phone: (206) 667-6364
Fax: (206) 667-4378
Research Associate Professor, Laboratory Medicine, University of Washington
Graduate Faculty, Laboratory Medicine, University of Washington
Director, Center for AIDS Research Immunology Core, University of Washington
Characterizing T cells induced by candidate vaccines using flow cytometry. Developing new assays to evaluate vaccine efficacy with HIV Vaccine Trials Network. Studies include examining T cell function at the single-cell level using advanced flow cytometric techniques; examples include T cell responses to vaccination and to viral infections such as CMV, EBV, HIV, and hepatitis B.
Affiliate Assistant Professor, Biostatistics, University of Washington
Statistical problems in biological assays, Biological sequence analysis, Stochastic optimization
Phone: (206) 667-1093
Fax: (206) 667-4378
Affiliate Associate Professor, Biostatistics, University of Washington
Statistical methods in biomarker evaluation for disease screening, surrogate endpoint identification, and treatment selection; genome-wide association studies and causal inference
Phone: (206) 667-4198
Fax: (206) 667-4378
Principal Staff Scientist, Vaccine and Infectious Disease Division
Principal Staff Scientist, Public Health Sciences Division
Unit Head, Biostatistical Collaborative Unit for Study Design and Data Analysis, Vaccine Immunology Statistical Center
Research focus include the design and analysis of clinical trials
Phone: (206) 667-5780
Fax: (206) 667-4378
Affiliate Associate Professor, Biostatistics, University of Washington
Graduate Faculty, Biostatistics, University of Washington
Clinical trials methodology; Vaccine evaluation; biomarker that predict an individual’s response to a given treatment and statistical analyses of vaccine trial data
Phone: (206) 667-6353
Fax: (206) 667-4378
Senior Staff Scientist, Public Health Sciences Division
Development of genetic statistical methodologies, including phylogenetic tree reconstruction from genetic sequences
Senior Vice President and Director, Vaccine and Infectious Disease Division
Professor of Medicine, University of Washington
Adjunct Professor, Pathobiology, Global Health, and Laboratory Medicine, University of Washington
Research centers on developing an HIV vaccine and investigating the complex relationship between HIV and the immune system and the influence of antiretroviral therapy.
Senior Staff Scientist, Public Health Sciences Division
Research focus includes analysis of HIV-1 CFSE assay data, cross-protocol analysis of DNA and Pox exploratory analysis and statistical methods for viral load set points
Phone: (206) 667-7008
Fax: (206) 667-4378