Vaccine and Infectious Disease Division

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Laboratories inside the Vaccine and Infectious Disease Division (VIDD), Fred Hutchinson Cancer Research Center

On the path to a new-generation malaria vaccine

mosquito

Photo by iStock

Researchers may be one step closer to a truly effective malaria vaccine, a new study suggests. A genetically modified malaria parasite worked as designed in its first human clinical trial, causing neither malaria nor serious safety problems in the 10 people who volunteered to be infected. It also stimulated an immune response that holds out promise of a more protective vaccine than the single candidate now in pilot studies

The Phase 1 study by scientists at Fred Hutchinson Cancer Research Center VIDD and the Seattle-based Center for Infectious Disease Research, or CIDR, was published Wednesday in the journal Science Translational Medicine.

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