Health Disparities Research Center

Disparities Projects

 

Partnership for the Advancement of Cancer Research, Pilot Project 1: Where Health and Horticulture Intersect: A Navajo Wellness Collaboration 
Co-Investigators: 
Shirley Beresford (FHCRC), India Ornelas (UW), Kevin Lombard (NMSU)
Population Focus: Navajo, New Mexico
Specific Population: Navajo Men and Women
Study Focus: Nutrition, Gardening

This pilot project is part of an ongoing partnership with members of the Navajo Nation in New Mexico. The long-range goal of this cancer-related public health intervention is to increase vegetable and fruit consumption and general health among people of the Navajo Nation.

Guided by an adaptation of social cognitive theory, we plan jointly to develop community gardens and to provide culturally appropriate workshops with technical horticultural support to augment these garden projects through a phased collaborative intervention in Navajo communities. Aspects of Navajo culture and traditional practices will be integrated into the intervention activities. Ultimately, we plan to estimate the effects of an integrated intervention on gardening and fruit and vegetable consumption, as well as, the effects on self-monitoring, self-efficacy, behavioral capability, and social norms related to gardening and vegetable and fruit consumption.

 This project will lay the groundwork, including specification of the intervention and of the outcome measures, for an R01 type proposal to formally evaluate the effectiveness of the intervention with a group randomized design. In the pilot, using a quasi-experimental design, we will obtain estimates of effect size and variability for use in determining the sample size for the R01. This proposal is directly responsive to the overall goal of the NMSU/FHCRC partnership: it will increase the capacity of NMSU to conduct cancer research in a competitive environment and attention at FHCRC to cancer-related health disparities research.

 

Screening Mammography and Latinas: A Multilevel Intervention 
Investigator:
 Shirley Beresford 
Population Focus:
 Hispanic/Latino 
Specific Population:
 Hispanic women 
Study Focus:
 Screening

An intervention project that seeks to increase screening for breast cancer among Latinas. Its goal is to address multi-level social determinants to both increase screening and to decrease barriers to screening. It will examine the influence of neighborhood characteristics and community cohesion on breast cancer screening. 

 

Addressing Psychosocial Disparities in Rural Hispanic Cancer Survivors 
Investigator:
 Rachel Ceballos 
Population Focus:
 Hispanic/Latino 
Specific Population:
 Hispanic breast and reproductive cancer survivors 
Study Focus:
 Survivorship

To develop a Spanish-language support program based in Social-Cognitive Theory for rural Hispanic survivors of female reproductive cancer and to evaluate the program using psychosocial and biological outcomes. 

 

Sisters-Healing-Advocating-Praising-Empowering-Sisters (SHAPES)
Investigator:
 Rachel M. Ceballos, Yamile Molina
Community advocates: Jacci Thompson-Dodd, Bridgette Hempstead-Richardson, Shauna Weatherby, Arthur Walker, Edree Allen-Agbro
Population Focus: Women who identify as African American, Black, and/or of African descent
Specific Population: Women who identify as African American, Black, and/or of African descent who have received an abnormal mammogram result
Study Focus: Abnormal mammogram as well as diagnosis/treatment experiences

FHCRC staff and affiliates, including community advocates, conducted a qualitative study to address the experiences of women who identify as African American, Black, and/or of African descent when they receive an abnormal mammogram result. We are especially interested in comparing and contrasting their experiences with stressors, coping strategies, and healthcare experiences relative to non-Latina White and Latina women as well as assessing the variation in experiences among women who identify differently within this group. We have recently submitted a paper for review concerning medical advocacy and supportive environments for African American/Black/of African descent women after an abnormal mammogram result. We are currently analyzing similarities and differences in stressors and coping strategies among non-Latina White, Latina, and African American/Black/of African descent women.

 

Indigenous Wellness Research Institute (IWRI) 
Investigator: 
Bonnie Duran 
Population Focus: 
American Indian/Alaska Native 
Specific Population: 
AI/AN 
Study Focus: 
Other

Aimed at marshaling community, tribal, academic, and governmental resources toward innovative, culture-centered interdisciplinary, collaborative social and behavioral research and education. 

 

NARCH V- Research for Change: Cross-Site Multicultural Community-Based Participatory Research
Investigator: 
Bonnie Duran 
Population Focus: 
American Indian/Alaska Native 
Specific Population: 
AI/AN 
Study Focus: 
Other

An in-depth investigation of promoters and barriers to Community-Based Participatory Research in AI/AN communities and other under-served populations in order to improve health status and health equity 

 

Collaboration for a Healthy Community
Investigator
: Linda Ko & Cynthia Perry 
Population Focus: Lower Yakima Valley communities in Eastern Washington 
Focus: Childhood obesity

To develop an obesity prevention campaign to promote youth obesity awareness and control using community-based participatory research.

 

Colon Health Communication within Social Networks
Investigator:
 Linda Ko
Population: Hispanic/Latino adults from Eastern Washington
Focus: Health communication

To examine how communication around colorectal cancer screening is disseminated through social networks.

 

Alliance for Reducing Cancer, Northwest: Cancer Prevention and Control Research Network Investigator: Linda Ko
Population: Asians and Latinos
Focus: Health disparities

To implement and disseminate evidence-based intervention to address health disparities experienced by limited English proficient populations.

 

Food & Fitness Environment 
Investigator:
Linda Ko
Population: Hispanic/Latino adults from Eastern Washington
Focus: Food environment  

To examine socioeconomic status (SES) and environmental variables predict subsequent changes in energy intakes, diet quality and cost, physical activity, and body weight.

 

Risk Factors for Triple-negative and HER2-overexpressing Breast Cancer among Hispanic Women and Non-Hispanic Women 
Investigator:
 Christopher Li 
Population Focus:
 Hispanic/Latino 
Specific Population:
 Hispanic women 
Study Focus:
 Prevention

To explore the reproductive factors, anthropometric measures, mammographic density, and family history of breast cancer, related to risks of TN and H2E breast cancer in Hispanic v. non-Hispanic women.

 

Investigator: Hannah Linden
Population Focus: All
Study Focus: Clinical Trials

Working with HMC and SCCA to improve cancer care and access to clinical trials for vulnerable patients; collaborates with Ethnomed and Community House Calls programs

 

The CARE Study - A multicenter study of risk factors for breast cancer in White and Black U.S. women
Investigator: 
Kathi Malone
Population Focus: African American women
Study Focus: 
Genetics, Screening

The CARE Study is a multicenter study (other sites: Los Angeles, Philadelphia, Detroit and Atlanta) in White and Black women ages 35-64 designed to assess a number of factors including racial and age-related variation in effects of breast cancer risk factors, mammographic efficacy, and genetic susceptibility. Malone led the genetic susceptibility work which assessed risk in relation to mutations in the BRCA1/2 genes as well as in other genes. This was the first large-scale (and population-based) effort to characterize the prevalence and risk related to BRCA1/2 in African-American women (Malone, 2006). Analyses and manuscript development are ongoing. 

 

Investigator: Peggy Porter
Population Focus: Hispanic/Latino
Specific Population: Hispanic women
Study Focus: Genetics

Primary aim is to determine the relationship between tumor subtype and ancestry in Hispanic women with breast cancer by a.) determining the tumor subtype by gene expression array; b.) determining ancestry through ancestry informative markers (AIMs); and c.) comparing tumor subtype with individual ancestry as defined through AIMs. 

 

A Multi-State Study of Cancer Treatment and Outcomes among American Indians
Investigator:  Scott Ramsey
Population Focus: American Indian/Alaska Native
Specific Population: AI/AN cancer patients
Study Focus: Treatment, Survivorship

This project links clinical information, health care claims, and outcomes data for AI/AN cancer patients in CA, OR and WA. This resource will be used to evaluate adherence to cancer treatment and post-treatment surveillance for AI/AN Medicaid and Medicare enrollees diagnosed with lung, breast, colorectal, prostate, cervical, ovarian and stomach cancer. 

 

The Legacy Project
Investigator:
Jeff Schouten
Population Focus: African American, Hispanic/Latino, Native Americans, Women, Men who have sex with men, Transgender people
Study Focus: HIV/AIDS

The Legacy Project seeks to increase knowledge about HIV clinical prevention and therapeutic research, cure research, scientific literacy, and participation in HIV/AIDS Clinical Research among the most disparately impacted communities in the United States.

The Legacy Project works nationally to increase awareness of and build support for HIV prevention and treatment clinical and behavioral research by addressing factors that influence participation of historically underrepresented communities. The Legacy Project achieves its core mission through ongoing and strategic engagement, collaboration, education, and scientific investigation. With a team of diverse, skilled and devoted staff, the Legacy Project works to cultivate and enhance partnerships and relationships among the National Institutes of Health (NIH) HIV/AIDS Clinical Trials Networks and research sites, research and academic institutions, governmental agencies, community-based organizations and affiliates, while ensuring a commitment to capacity building for communities and populations most impacted by the HIV epidemic in the United States.

 

Partnership for the Advancement of Cancer Research NMSU - FHCRC: Summer Undergraduate Internship Project
Investigator: 
Julian Simon
Population: all
Specific Population: all

The Summer Undergraduate Research Program [SURP] is an intensive, nine-week internship designed to provide research experience and mentorship for undergraduate students who are interested in biological research. Under the guidance of a faculty mentor, students will complete an independent research project and present their findings at a competitive poster session

 

Development of a Cervical Cancer Screening Program for Refugee Women 
Investigator:
Vicky Taylor 
Population Focus: Asian 
Specific Populations:  Bhutanese American and Burmese American 
Study Focus: Prevention, Other

The long-term study goal is to evaluate a contextually relevant cervical cancer control program targeting refugee women during their resettlement. The program would involve use of culturally tailored videos, as well as logistic assistance accessing screening services (i.e. navigation). Refugee resettlement organization personnel would implement the intervention components. This developmental proposal has the following objectives: (1) Through focus group research, identify and describe cervical cancer screening barriers and facilitators among refugee women; (2) Develop culturally tailored educational and motivational cervical cancer screening videos (that could be used in multiple resettlement settings); (3) Pilot test the intervention program (video use and logistic assistance), and conduct an exploratory evaluation of the program; and (4) Through key informant interviews with representatives from refugee resettlement organizations, assess refugee organizations readiness to implement our intervention program during the resettlement process.

 

Cancer Center Support Grant Administrative Supplement Activities
Investigator:
Beti Thompson, Gary Gilliland
Population Focus: Racially/Ethnically Diverse Populations
Study Focus: Clinical Trials

The overall goals of this supplement are to build upon previous efforts by parent grant programs to expand research with underserved populations and to find ways to increase inclusion of minorities in research and clinical trials in the cancer center catchment area.

 

Community Network Program Center (CNPC) Administrative Supplement Activities
Investigator:
Beti Thompson
Population Focus: Hispanic/Latino, Medically Underserved
Study Focus: Cervical Cancer Screening Education

In this administrative supplement, we will: 1) identify gaps and barriers in the delivery of information about Pap and HPV test results for cervical cancer screening among Yakima Valley Farm Workers Clinic clients, 2) develop culturally appropriate messages and content for three different channels of information (a digital story, a fotonovela, and a radionovela), to help women gain an understanding about HPV and what a positive HPV test result means, and 3) field test the three sources of information (digital story, fotonovela and radionovela) to define the best methods for educating women about HPV and HPV test results. 

 

Center for Hispanic Health Promotion: Reducing Cancer Disparities 
Investigator:
 Beti Thompson 
Population Focus
: Hispanic/Latino, American Indian/Alaska Native 
Specific Population:
 Native American, Hispanic 
Study Focus:
 All

It is the long-term goal of the Center for Hispanic Health Promotion:  Reducing Cancer Disparities to use a Community-Based Participatory Research (CBPR) approach to reduce the cancer disparities experienced by Hispanics and American Indians in Yakima and Franklin County of Washington State.  Our short-term objectives are to:  1. Develop and enhance our existing relationships with community partners in both counties to reduce cancer disparities among Latinos and members of the Yakama Nation (Administrative Core); 2. Increase health promotion outreach and cancer screening activities among Latinos and members of the Yakama Nation (Outreach Core); 3. Increase cervical cancer screening among Latinas using a rigorous research project (Research Core); 4. Develop and assess the feasibility of a sustainable support system for cancer patients and survivors (Research Core); and 5. Train junior investigators, especially underrepresented minorities, in grant writing and CBPR to reduce cancer disparities (Training Core). 

 

Investigator: Beti Thompson 
Population Focus
: Hispanic/Latino, AI/AN, Medically Underserved
Study Focus:
 Healthy Living/Cancer Prevention

Partner with organizations in the Yakima Valley of WA State to implement a healthy living campaign which includes: a Quit & Win smoking cessation contest and nutrition classes with a physical activity component. 

 

Geographical Management of Programs (GMaP) 
Investigator:
 Beti Thompson 
Population Focus:
 All 
Study Focus: 
Cancer Health Disparities Research and Training

GMaP is a systematic and comprehensive approach to facilitating collaboration, cooperation, information- and resource-sharing, and capacity-building among cancer health disparities researchers, trainees, outreach workers, and organizations, with the key goal of advancing cancer health disparities research and training.

 

Health Disparities Research Center 
Investigator: 
Beti Thompson 
Population Focus: 
All 
Study Focus: 
All

The mission of the Health Disparities Research Center (HDRC) is to create an initiative designed to enhance collaboration with and among Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance programs and systems for the purpose of eliminating cancer health disparities. 

 

Partnership for a Hispanic Diabetes Prevention Program 
Investigator: 
Beti Thompson 
Population Focus: 
Hispanic/Latino 
Specific Population: 
Hispanic 
Study Focus: 
Other

The home-based intervention delivered by Community Health workers (promotoras) was associated with a clinically and statistically significan reduction in HbA1c levels in Hispanic adults with HbA1c levels higher than 6%. The immediate intervention group showed a significant improvement in HbA1c scores compared with the delayed intervention group. 

Citation for the published results: 
Duggan C, Carosso E, Mariscal N, Islas I, Ibarra G, Holte, S, et al. Diabetes Prevention in Hispanics: Report from a Randomized Controlled Trial. Prev Chronic Dis 2014; 11:130119. DOI: hhtp://dx.doi.org/10.5888/pcd11.130119 

 

Partnership for the Advancement of Cancer Research NMSU - FHCRC
Investigator:
Beti Thompson
Population Focus:
All
Study Focus:
All

The overall goal of the FHCRC/NMSU U54 partnership is to continue to build upon increasing cancer research capacity at NMSU and to increase knowledge and attention to cancer-related health disparities research at the FHCRC. To help achieve this overall goal, our specific aims are to:  1.) Conduct a diverse portfolio of cancer research projects. 2.) Maintain, strengthen, and evaluate our effective training programs for current and future underserved scientists. The Integrated Training and Evaluation Core (ITREC) will integrate all the U54-spnsored training components. 3.) Implement cancer-related public health interventions in underserved communities. As part of this aim, we will conduct research and disseminate evidence-based practices. To achieve these aims, the U54 sponsors a broad portfolio of innovative projects and cores that promote the development of cancer research, training, and outreach.  

 

Understanding and Preventing Breast Cancer Disparities in Latinas
Investigator: Beti Thompson
Population Focus: Hispanic/Latino
Specific Population: Latina women
Study Focus: Genetics, Screening

The long-term goal of the project is to understand the precursors of breast cancer in Latinas, understand the types of breast cancer found in this population, and develop and implement a comprehensive screening program to improve early detection of the disease. 

 

 

 

Updated: March 2016