Health Disparities Research Center

Disparities Projects

Enhancing and Teaching [EAT] 5 for Life Project
Investigator:
Shirley Beresford
Population Focus:
All
Study Focus:
Nutrition

The Enhancing And Teaching [EAT] 5 for Life Project is funded by the National Cancer Institute. This study is a randomized trial to evaluate the effectiveness of an intervention to maintain change in companies that have already received an intervention to increase fruit and vegetable consumption (the Seattle 5 a Day Worksite Program).The goal of the EAT 5 for Life Study is to continue the behavior of increased fruit and vegetable consumption for long term, without research office dependence. The intervention is designed to help worksites adopt 5 a Day activities as part of their standard operating procedures in order to reinforce and maintain dietary behavior change. The randomized controlled trial involves a majority of the same worksites that participated in the Seattle 5 a Day Worksite Project. Seventeen of the original Seattle 5 a Day intervention worksites were randomized to maintenance intervention or control. Eleven of the original comparison worksites and eleven new worksites received the Seattle 5 a Day Intervention. Thirty-nine worksites were randomized to maintenance or control. Participating worksites are in King, Snohomish and Pierce counties.

All companies are primarily manufacturing and service industries. EAT 5 for Life maintenance intervention worksites reestablished Employee Advisory Boards (EAB). These groups of employees were trained to identify the needs of their worksite in order to implement 5 a Day activities best suited for their worksite. Hutch staff train EAB members and provide technical assistance to support the implementation of work-sponsored dietary activities. The evaluation compares change at the worksite level in servings of fruits and vegetables, assessed using independent cross-sectional samples of employees at two time points: the new baseline and 24-month follow-up

 

Move and Moderate in Balance (MOVE'M): A TREC Worksite Health Study
Investigator: 
Shirley Beresford 
Population Focus: 
All 
Study Focus: 
Nutrition, Physical Activity

This study recruited small worksites located in underserved communities in south-central Seattle. Overall objective is to develop and evaluate an intervention that will maintain or decrease body mass index by influencing the worksite environment, including policies and procedures, by increasing worksite access to healthy foods and physical activity opportunities and promoting individual behavior change, through increasing awareness of energy balance; building a physical activity intervention that will promote increased levels of energy expenditure through the combination of increased daily physical activity and regular structured exercise; and building a dietary intervention that will promote decreased calorie intake. 

 

Screening Mammography and Latinas: A Multilevel Intervention 
Investigator:
 Shirley Beresford 
Population Focus:
 Hispanic/Latino 
Specific Population:
 Hispanic women 
Study Focus:
 Screening

An intervention project that seeks to increase screening for breast cancer among Latinas. Its goal is to address multi-level social determinants to both increase screening and to decrease barriers to screening. It will examine the influence of neighborhood characteristics and community cohesion on breast cancer screening. 

 

Addressing Psychosocial Disparities in Rural Hispanic Cancer Survivors 
Investigator:
 Rachel Ceballos 
Population Focus:
 Hispanic/Latino 
Specific Population:
 Hispanic breast and reproductive cancer survivors 
Study Focus:
 Survivorship

To develop a Spanish-language support program based in Social-Cognitive Theory for rural Hispanic survivors of female reproductive cancer and to evaluate the program using psychosocial and biological outcomes. 

 

Transition from Patient to Survivor: Patient Navigation in African-Americans
Investigator:
 Rachel Ceballos 
Community Advocates: Jacci Thompson-Dodd, Bridgette Hempstead-Richardson, Shauna Weatherby, Arthur Walker, Edree Allen-Agbro
Population Focus: African American 
Specific Population: African American breast cancer survivors
Study Focus: Survivorship

To assess the emotional and information support needs and resources of African American cancer survivors in the Puget Sound region. Also, to assess what factors are associated with those needs and resources. To develop a culturally-competent survivor support program for African-African breast cancer survivors 

 

Sisters-Healing-Advocating-Praising-Empowering-Sisters (SHAPES)
Investigator:
 Rachel M. Ceballos, Yamile Molina
Community advocates: Jacci Thompson-Dodd, Bridgette Hempstead-Richardson, Shauna Weatherby, Arthur Walker, Edree Allen-Agbro
Population Focus: Women who identify as African American, Black, and/or of African descent
Specific Population: Women who identify as African American, Black, and/or of African descent who have received an abnormal mammogram result
Study Focus: Abnormal mammogram as well as diagnosis/treatment experiences

FHCRC staff and affiliates, including community advocates, conducted a qualitative study to address the experiences of women who identify as African American, Black, and/or of African descent when they receive an abnormal mammogram result. We are especially interested in comparing and contrasting their experiences with stressors, coping strategies, and healthcare experiences relative to non-Latina White and Latina women as well as assessing the variation in experiences among women who identify differently within this group. We have recently submitted a paper for review concerning medical advocacy and supportive environments for African American/Black/of African descent women after an abnormal mammogram result. We are currently analyzing similarities and differences in stressors and coping strategies among non-Latina White, Latina, and African American/Black/of African descent women.

 

Indigenous Wellness Research Institute (IWRI) 
Investigator: 
Bonnie Duran 
Population Focus: 
American Indian/Alaska Native 
Specific Population: 
AI/AN 
Study Focus: 
Other

Aimed at marshaling community, tribal, academic, and governmental resources toward innovative, culture-centered interdisciplinary, collaborative social and behavioral research and education. 

 

NARCH V- Research for Change: Cross-Site Multicultural Community-Based Participatory Research
Investigator: 
Bonnie Duran 
Population Focus: 
American Indian/Alaska Native 
Specific Population: 
AI/AN 
Study Focus: 
Other

An in-depth investigation of promoters and barriers to Community-Based Participatory Research in AI/AN communities and other under-served populations in order to improve health status and health equity 

 

Collaboration for a Healthy Community
Investigator
: Linda Ko & Cynthia Perry 
Population Focus: Lower Yakima Valley communities in Eastern Washington 
Focus: Childhood obesity

To develop an obesity prevention campaign to promote youth obesity awareness and control using community-based participatory research.

 

Colon Health Communication within Social Networks
Investigator:
 Linda Ko
Population: Hispanic/Latino adults from Eastern Washington
Focus: Health communication

To examine how communication around colorectal cancer screening is disseminated through social networks.

 

Nuestras Comidas (Our Meals)
Investigator: 
Linda Ko
Population: Hispanic/Latino families in the Seattle metropolitan area
Focus: Obesity

To develop and test a healthy eating intervention program focused on nutrition education, healthy cooking, skill building, and accessibility of healthy food using community-based participatory research. 

 

SORI: Voices of Older Asian Immigrants Aging in America
Investigator: 
Linda Ko
Population: Asian care givers
Focus:  Aging

To bring awareness to the community of the challenges and barriers of caring for an aging parent, and to mobilize resources to address these issues. 

 

Risk Factors for Triple-negative and HER2-overexpressing Breast Cancer among Hispanic Women and Non-Hispanic Women 
Investigator:
 Christopher Li 
Population Focus:
 Hispanic/Latino 
Specific Population:
 Hispanic women 
Study Focus:
 Prevention

To explore the reproductive factors, anthropometric measures, mammographic density, and family history of breast cancer, related to risks of TN and H2E breast cancer in Hispanic v. non-Hispanic women.

 

Investigator: Hannah Linden
Population Focus: All
Study Focus: Clinical Trials

Working with HMC and SCCA to improve cancer care and access to clinical trials for vulnerable patients; collaborates with Ethnomed and Community House Calls programs

 

The CARE Study - A multicenter study of risk factors for breast cancer in White and Black U.S. women
Investigator: 
Kathi Malone
Population Focus: African American women
Study Focus: 
Genetics, Screening

The CARE Study is a multicenter study (other sites: Los Angeles, Philadelphia, Detroit and Atlanta) in White and Black women ages 35-64 designed to assess a number of factors including racial and age-related variation in effects of breast cancer risk factors, mammographic efficacy, and genetic susceptibility. Malone led the genetic susceptibility work which assessed risk in relation to mutations in the BRCA1/2 genes as well as in other genes. This was the first large-scale (and population-based) effort to characterize the prevalence and risk related to BRCA1/2 in African-American women (Malone, 2006). Analyses and manuscript development are ongoing. 

 

Metabolic Response to Western vs. Indigenous Diets in Hispanic Women 
Investigator: 
Marian Neuhouser 
Population Focus: 
Hispanic/Latino 
Specific Population: 
Mexican and Mexican-American women 
Study Focus: 
Genetics, Nutrition

To test the metabolic response to Western and Indigenous Mexican diets in Hispanic women and investigate whether ancestral genetic variation mediates the response to each diet. 

 

Inflammation Markers in Breast Tissue and Body Mass Index and in Breast Cancer
Investigator: Marian Neuhouser 
Population Focus: Hispanic/Latino 
Specific Population: Mexican and Mexican-American women 
Study Focus: Genetics, Nutrition

 

Investigator: Peggy Porter
Population Focus: Hispanic/Latino
Specific Population: Hispanic women
Study Focus: Genetics

Primary aim is to determine the relationship between tumor subtype and ancestry in Hispanic women with breast cancer by a.) determining the tumor subtype by gene expression array; b.) determining ancestry through ancestry informative markers (AIMs); and c.) comparing tumor subtype with individual ancestry as defined through AIMs. 

 

A Multi-State Study of Cancer Treatment and Outcomes among American Indians
Investigator:  Scott Ramsey
Population Focus: American Indian/Alaska Native
Specific Population: AI/AN cancer patients
Study Focus: Treatment, Survivorship

This project links clinical information, health care claims, and outcomes data for AI/AN cancer patients in CA, OR and WA. This resource will be used to evaluate adherence to cancer treatment and post-treatment surveillance for AI/AN Medicaid and Medicare enrollees diagnosed with lung, breast, colorectal, prostate, cervical, ovarian and stomach cancer. 

 

The Legacy Project
Investigator: 
Jeff Schouten
Population Focus: African American, Hispanic/Latino, Native Americans, Women, Men who have sex with men, Transgender people
Study Focus: HIV/AIDS

The Legacy Project's mission is to build trust and collaboration between historically underrepresented communities most impacted by the domestic HIV epidemic, researchers, and research institutions; enhance cultural competency; and initiate scientific investigation to increase clinical research participation. 

The Legacy Project works nationally to increase awareness of and build support for HIV prevention and treatment clinical and behavioral research by addressing factors that influence participation of historically underrepresented communities. The Legacy Project achieves its core mission through ongoing and strategic engagement, collaboration, education, and scientific investigation. With a team of diverse, skilled and devoted staff, the Legacy Project works to cultivate and enhance partnerships and relationships among the National Institutes of Health (NIH) HIV/AIDS Clinical Trials Networks and research sites, research and academic institutions, governmental agencies, community-based organizations and affiliates, while ensuring a commitment to capacity building for communities and populations most impacted by the HIV epidemic in the United States. 

 

Partnership for the Advancement of Cancer Research NMSU - FHCRC: Summer Undergraduate Internship Project
Investigator: 
Julian Simon
Population: all
Specific Population: all

The Summer Undergraduate Research Program [SURP] is an intensive, nine-week internship designed to provide research experience and mentorship for undergraduate students who are interested in biological research. Under the guidance of a faculty mentor, students will complete an independent research project and present their findings at a competitive poster session

 

HPV Vaccination in a Cambodian Community 
Investigator: 
Vicky Taylor 
Population Focus: 
Asian 
Specific Population: 
Cambodian American 
Study Focus: 
Prevention, Other

The study goal is to conduct mixed-methods research that could be used to inform the development, implementation, and evaluation of culturally appropriate HPV vaccination interventions targeting Cambodian women with daughters in the 9-17 age group. The primary objectives are: to provide qualitative data relevant to the promotion of HPV vaccine use in Cambodian communities; and quantitative data about the uptake of HPV vaccination among Cambodian adolescents, as well as correlates of HPV vaccine uptake. A recent review of HPV vaccine surveillance in the US found no publications addressing the reliability of self-reported HPV vaccine uptake. The secondary objective is to assess the test-retest reliability of survey measures addressing HPV vaccine uptake in a Cambodian study group. 

 

Cancer Center Support Grant Administrative Supplement Activities
Investigator: 
Beti Thompson, Larry Corey
Population Focus: Hispanic/Latino, Native Americans, Medically Underserved
Study Focus: Breast Cancer Prevention

Implement pilot projects in the Yakima Valley of WA State to address health disparities around breast cancer through the use of home health parties, health fairs, and a Photovoice project. 

 

Investigator: Beti Thompson, Larry Corey
Population Focus: Community-based organizations serving medically underserved
Study Focus: Education

Teach community-based organizations in WA State how to write grants to implement programs with/for medically underserved populations through a two-day grant writing workshop. Develop an RFA for $5,000 that CBOs can respond to.  Fund 3 - 4 organizations to implement their projects.

  

Center for Child Environmental Health Risks Research: Reducing Pesticide Exposure in Children of Farm Workers 
Investigator:
 Beti Thompson 
Population Focus
: All 
Study Focus
: Other

The specific aim of this study is to characterize the seasonal variability of organophosphate (OP) exposure across our cohort by sampling at times of peak OP usage and by evaluating OP metabolite profiles across time during these seasons.

 

Center for Hispanic Health Promotion: Reducing Cancer Disparities 
Investigator:
 Beti Thompson 
Population Focus
: Hispanic/Latino, American Indian/Alaska Native 
Specific Population:
 Native American, Hispanic 
Study Focus:
 All

It is the long-term goal of the Center for Hispanic Health Promotion:  Reducing Cancer Disparities to use a Community-Based Participatory Research (CBPR) approach to reduce the cancer disparities experienced by Hispanics and American Indians in Yakima and Franklin County of Washington State.  Our short-term objectives are to:  1. Develop and enhance our existing relationships with community partners in both counties to reduce cancer disparities among Latinos and members of the Yakama Nation (Administrative Core); 2. Increase health promotion outreach and cancer screening activities among Latinos and members of the Yakama Nation (Outreach Core); 3. Increase cervical cancer screening among Latinas using a rigorous research project (Research Core); 4. Develop and assess the feasibility of a sustainable support system for cancer patients and survivors (Research Core); and 5. Train junior investigators, especially underrepresented minorities, in grant writing and CBPR to reduce cancer disparities (Training Core). 

 

Community Network Program Center (CNPC) Administrative Supplement Activities
Investigator:
 Beti Thompson 
Population Focus
: Hispanic/Latino, Medically Underserved
Study Focus:
 Digital Storytelling

Work with community members in the Yakima Valley to WA State to create digital stories to educate audiences about health disparities and advocate for change. 

 

Investigator: Beti Thompson 
Population Focus
: Hispanic/Latino, AI/AN, Medically Underserved
Study Focus:
 Healthy Living/Cancer Prevention

Partner with organizations in the Yakima Valley of WA State to implement a healthy living campaign which includes: a Quit & Win smoking cessation contest and nutrition classes with a physical activity component. 

 

Geographical Management of Programs (GMaP) 
Investigator:
 Beti Thompson 
Population Focus:
 All 
Study Focus:
 Screening, Prevention

To develop state-of-the-art regional networks dedicated to the support and management of cancer health disparities research, training and infrastructure. The GMaP initiative has provided funding to 4 community organizations across the western region to conduct colorectal cancer prevention and screening education to underrepresented populations. Additionally, a series of biospecimen collection/donation trainings have been conducted throughout GMaP Region 6 (AK, WA, OR, CA, ID, NV, MT, HI, American Samoa and Guam).  These trainings provide basic information about the biospcimen collection process and the importance of biospecimens in research.

 

Health Disparities Research Center 
Investigator: 
Beti Thompson 
Population Focus: 
All 
Study Focus: 
All

The mission of the Health Disparities Research Center (HDRC) is to create an initiative designed to enhance collaboration with and among Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance programs and systems for the purpose of eliminating cancer health disparities. 

 

Partnership for a Hispanic Diabetes Prevention Program 
Investigator: 
Beti Thompson 
Population Focus: 
Hispanic/Latino 
Specific Population: 
Hispanic 
Study Focus: 
Other

The home-based intervention delivered by Community Health workers (promotoras) was associated with a clinically and statistically significan reduction in HbA1c levels in Hispanic adults with HbA1c levels higher than 6%. The immediate intervention group showed a significant improvement in HbA1c scores compared with the delayed intervention group. 

Citation for the published results: 
Duggan C, Carosso E, Mariscal N, Islas I, Ibarra G, Holte, S, et al. Diabetes Prevention in Hispanics: Report from a Randomized Controlled Trial. Prev Chronic Dis 2014; 11:130119. DOI: hhtp://dx.doi.org/10.5888/pcd11.130119 

 

Partnership for the Advancement of Cancer Research NMSU - FHCRC
Investigator:
Beti Thompson
Population Focus:
All
Study Focus:
All

The overall goal of the FHCRC/NMSU U54 partnership is to continue to build upon increasing cancer research capacity at NMSU and to increase knowledge and attention to cancer-related health disparities research at the FHCRC. To help achieve this overall goal, our specific aims are to: 1.) Conduct a diverse portfolio of cancer research projects. 2.) Maintain, strengthen, and evaluate our effective training programs for current and future underserved scientists. The Integrated Training and Evaluation Core (ITREC) will integrate all the U54-spnsored training components. 3.) Implement cancer-related public health interventions in underserved communities. As part of this aim, we will conduct research and disseminate evidence-based practices. To achieve these aims, the U54 sponsors a broad portfolio of innovative projects and cores that promote the development of cancer research, training, and outreach.  

 

Understanding and Preventing Breast Cancer Disparities in Latinas
Investigator: Beti Thompson
Population Focus: Hispanic/Latino
Specific Population: Latina women
Study Focus: Genetics, Screening

The long-term goal of the project is to understand the precursors of breast cancer in Latinas, understand the types of breast cancer found in this population, and develop and implement a comprehensive screening program to improve early detection of the disease. 

 

Research Supplements to Promote Diversity in Health-Related Research
Investigator:
Beti Thompson
Population Focus: All
Study Focus: All

The overall goal of this research supplement is to provide experience and support to an underrepresented student in conducting health promotion and education activities in underserved communities in the Yakima Valley.