Ramesh Rengan, MD, PhD

Ramesh Rengan, MD, PhD

Professor, Department of Radiation Oncology
University of Washington School of Medicine
Associate Member
Clinical Research Division
Medical Director, SCCA Proton Therapy Center
Seattle Cancer Care Alliance


University of Michigan, 1992, B.Sc (Chemistry)
University of Michigan, 1995, M. Sc (Biological Chemistry)
University of Michigan, 2001, PhD (Biological Chemistry)
University of Michigan, 2001, MD
Memorial Sloan-Kettering Cancer Center, 2006, Residency (Radiation Oncology)

Research Focus

The overall objective of Dr. Rengan’s research centers on approaches to improve the therapeutic ratio in solid tumors to ionizing photon or proton radiation. His active area of current research is in pre-clinical and clinical strategies to utilize radiation to trigger an anti-tumor immune response in patients with advanced malignancies. He also has an interest in healthcare disparities and expanded access to radiation treatment in low-resource environments. In summary, his research spans across the domains of:

  • Photon- and Proton based radiation regimens to trigger an immune response to augment immunotherapeutic platforms in solid malignancies including NSCLC, melanoma, lymphoma, and renal cell carcinoma
  • Development of biomarkers of immunologic and tumor response to ionizing radiation in solid tumors
  • Functional imaging to interrogate tumor and normal tissue response to ionizing radiation in solid tumors
  • Impact of healthcare resources on radiation-related outcome in solid tumors

Clinical Expertise

Dr. Rengan’s clinical expertise is in the treatment of thoracic malignancies, including NSCLC, small cell lung cancer, thymoma, and mesothelioma as well as melanoma and renal cell carcinoma. Additionally, he has clinical expertise in the use of proton and particle beam therapy in the management of solid tumors.

Current Studies

1. Radiation and Ipilimumab in advanced melanoma CC 9031

2. Radiation, Nelfinavir, and Nivolumab in advanced melanoma, renal cell carcinoma, and NSCLC CC9712

3. Radiation and atezolizumab in advanced NSCLC CC 9490

4.  Functional Imaging-based Dose Escalation in Locally Advanced NSCLC CC 9599

5.  Proton vs Photon Beam Radiotherapy in Locally Advanced NSCLC NRG 1308

Related News

Additional Links & Information

Related Labs & Projects

View all labs & projects >
Ramesh Rengan, MD, PhD

Contact Information

(206) 306-2814
(206) 417-0347