PHS Program: Translational Research Program
Watson School of Biological Sciences, 2004, PhD (Biological Sciences)
The Paddison Lab uses functional genomics to probe the underlying biology of normal and cancerous stem/progenitor cells. We identify and characterize gene products affecting stem cell self-renewal, differentiation, proliferation, or survival through the use of CRISPR-Cas9 and RNAi technologies. For our cancer studies we create novel models of precision functional genomics directly in patient tumor isolates.