Translational Research Program Faculty

Translational Research Program

Translational Research Program Faculty

Contact information, projects, and CVs of Molecular Diagnostics faculty members can be accessed using the links below. General descriptions of Translational Research Program projects are found on the Projects page.

Co-Program Heads: Paul Lampe, PhD and Christopher Li, MD, PhD

Alphabetical Listing:

Select a letter to display a list of Faculty members
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Understanding behavioral issues related to cancer intervention and prevention strategies.
Phone: (206) 667-6684
Fax: (206) 667-7264
The Bielas Laboratory studies the fundamental and clinical implications of nuclear and mitochondrial DNA mutations in the pathogenesis of cancer and age-related disease.
Phone: (206) 667-3170
Fax: (206) 667-2537
Quantitative studies of cell signaling and variation
Phone: (206) 667-1799
Fax: (206) 667-6522
Full Member, Epidemiology, Public Health Sciences Division
Affiliate Professor, Otolaryngology: Head and Neck Surgery, University of Washington School of Medicine
Affiliate Professor, Epidemiology, University of Washington School of Public Health
Graduate School Faculty, Epidemiology, University of Washington School of Public Health
Etiology of tobacco-related cancers (head and neck cancer, lung cancer); etiology of hormone-related cancers (breast, endometrium, prostate, testes); prognostic gene signatures for oral cancer.
Phone: (206) 667-6644
Fax: (206) 667-2537
Assistant Member, Translational Research Program, Public Health Sciences Division
Assistant Member, Human Biology Division
The Cheung lab studies the cellular and molecular biology of tumor cell clusters and their role in breast cancer metastasis.
Phone: (206) 667-6276
Gynecological oncology; ovarian cancer.
Phone: (206) 667-7459
Fax: (206) 215-6201
Associate Member, Clinical Research Division
Phone: (206) 667-5077
Fax: (206) 606-2054
Assistant Member, Human Biology Division
Dr. Ghajar directs the Laboratory for the Study of Metastatic Microenvironments (LSM2). The goal of his research program is to understand how microenvironments within distant tissues regulate dormancy and growth of disseminated tumor cells (DTCs), and whether these niches convey chemoresistance to dormant DTCs. His belief is that solving these puzzles will allow the development of therapeutic regimens that eradicate dormant DTCs before they can develop into full-blown metastases.
Phone: (206) 667-7080
Fax: (206) 667-2537
Professor, Medicine, University of Washington
Director, Center for Accelerated Translation in Pancreas Cancer (CATPAC), Seattle Translational Tumor Research
Raisbeck Endowed Chair for Pancreatic Research, Clinical Research Division
The molecular and cellular mechanisms that drive the pathogenesis of pancreas cancer
Phone: (206) 667-6921
The Hockenbery lab studies programmed cell death (apoptosis) pathways that are defective in many cancer cells; and the role of cancer-cell metabolism in apoptosis, oncogene functions, and environmental/dietary risk factors, including excess supply of nutrients. After identifying cancer-selective targets, they carry out small-molecule screens for inhibitors to identify lead compounds as anticancer agents.
Phone: (206) 667-4611
Fax: (206) 667-6519
The Kemp Lab seeks to identify the next generation of targeted anticancer agents. We use a combination of high throughput functional genomic and small molecule screens, and genomic analysis applied to a range of isogenic and patient derived tumor models. We are discovering and validating novel drug targets and therapeutic options for multiple solid tumor types including pancreatic, ovarian, head and neck and breast cancer.
Phone: (206) 667-4252
Fax: (206) 667-5815
Member and Associate Director, Public Health Sciences Division
Cancer Prevention Program, Public Health Sciences Division
Controlled dietary studies, nutrition interventions and phytochemicals.
Phone: (206) 667-6580
Fax: (206) 667-7850
Intercellular communication and the control of cell growth.
Phone: (206) 667-5408
Fax: (206) 667-2537
Breast cancer etiology and outcomes.
Phone: (206) 667-7444
Fax: (206) 667-5948
Associate Member, Clinical Research Division
Clinical focus is bone marrow transplant pathology including accessing hematologic malignancy, graft-vs-host disease and infection in stem cell transplant patients.
Phone: (206) 606-1356
Fax: (206) 606-1345
Associate Member, Human Biology Division
The MacPherson Lab is focused on understanding the mechanisms through which cancer-mutated genes drive tumorigenesis. The lab studies small cell lung cancer and other solid tumors. We generate novel genetically engineered mouse models that we use to interrogate the biology underlying major cancer driver genes. We are particularly interested in understanding epigenetic regulators that are genetically mutated in human tumors.
Phone: (206) 667-6464
Fax: (206) 667-2917
Endowed Chair for Prostate Cancer Research, Fred Hutchinson Cancer Research Center
Research focus is the understanding the molecular, cellular and physiological events that lead to cancer initiation and progression. A particular emphasis involves hormonal carcinogenesis and prostate cancer with the goal of developing new strategies for diagnosis, prognosis and therapy.
Phone: (206) 667-3377
Fax: (206) 667-2917
Associate Member, Human Biology Division
The Paddison Lab uses functional genomics to probe the underlying biology of normal and cancerous stem/progenitor cells. We identify and characterize gene products affecting stem cell self-renewal, differentiation, proliferation, or survival through the use of CRISPR-Cas9 and RNAi technologies. For our cancer studies we create novel models of precision functional genomics directly in patient tumor isolates.
Phone: (206) 667-4312
Fax: (206) 667-4023
Alternations in cell proliferation and genetic instability in aging and in neoplastic progression
Phone: (206) 667-3761
Fax: (206) 667-5530
Phone: (765) 418-3200
The Reid Lab is focused on understanding the mechanisms by which environmental exposures (i.e. aspirin or other nonsteroidal antiinflammatory agents) affect the evolution of clones that lead to the development of esophageal adenocarcinoma in patients with Barrett's esophagus.
Fax: (206) 667-6192
Affiliate Member, Basic Sciences Division
Dr. Penny E. Petersen Memorial Chair for Lymphoma Research, Fred Hutchinson Cancer Research Center
Director of Molecular and Cellular Biology (MCB) Graduate Program, Fred Hutchinson Cancer Research Center
The Salama lab studies the gastric bacterial pathogen Helicobacter pylori, which infects half the world's population and can cause ulcers and gastric cancer.
Phone: (206) 667-1540
Fax: (206) 667-6524
Health Services Research Professor, University of Washington
Research on the promotion, surveillance and cost-effectiveness of cancer screening.
Phone: (206) 667-4677
Fax: (206) 667-7264