The MsFLASH network is coordinated by three principal investigators from Fred Hutch, University of Washington and the University of California.  Fred Hutch is also the data coordinating center for the network.

Dr. Guthrie is a senior biostatistician with 15 years of experience specializing in clinical trials. She has served as lead statistician for the MsFLASH network since its inception in 2008 and has been co-Principal Investigator at the MsFLASH Data Coordinating Center since 2013. As SWOG statistical faculty and previously as a member of the Clinical Research Division of Fred Hutch, she has served a key role in the design, analysis, and publication of numerous clinical research studies. She currently serves as the faculty statistician on the SWOG Gastrointestinal Cancers Committee and the Cancer Survivorship Committee, as well as an advisor to the National Cancer Institute through the GI Steering Committee. She provides independent expertise and oversight of multiple clinical trials through service on Data and Safety Monitoring Boards. She has authored over 100 peer-reviewed articles. Dr. Guthrie received her undergraduate degree in mathematics from Bates College, and her masters and doctoral degrees from the Department of Biostatistics at the University of Washington.

Andrea LaCroix, PhD

Andrea Z. LaCroix, PhD

  • Professor and Chief of Epidemiology
  • Director, Women's Health Center of Excellence
  • Family Medicine and Public Health
  • University of California - San Diego

Dr. LaCroix is currently Professor and Chief of Epidemiology in the Department of Family Medicine and Public Health at the University of California, San Diego. She is also the Director of the Women’s Health Center of Excellence at UCSD. She has an extensive research program devoted to studies on factors associated with healthy aging in postmenopausal women. She has conducted numerous randomized clinical trials and observational studies on the prevention of cancer, fracture, heart disease, and frailty in postmenopausal, as well as large, prospective studies of exceptional aging and maintaining function into later life.

Prior to joining the faculty of UCSD in October 2013, Dr. LaCroix was Co-Principal Investigator of the Women's Health Initiative (WHI) Clinical Coordinating Center at the Fred Hutchinson Cancer Research Center in Seattle, Washington. Her work within the WHI program includes evaluating the longterm effects of hormone therapy and calcium/Vitamin D supplementation on chronic disease outcomes including heart disease, cancer and fracture. She was also Co-Principal Investigator of the Data Coordinating Center for the Menopausal Symptoms: Finding Lasting Answers for Symptoms and Health (MsFLASH) clinical trials network, an NIA initiative to expedite the testing of new interventions for menopause symptoms. In addition, she continues work on healthy aging studies as a Senior Scientific Investigator at the Group Health Research Institute (GHRI) in Seattle where she also leads a NIA-funded T32 training program entitled, “Improving Healthcare for Aging Women.”

Dr. LaCroix received her doctoral degree in epidemiology from the University of North Carolina at Chapel Hill in 1984, and completed a postdoctoral fellowship in cardiovascular disease at The Johns Hopkins University in Baltimore, MD in 1985. Before coming to Seattle, WA in 1989, Dr. LaCroix was a federal government epidemiologist at the National Center for Health Statistics and then the National Institute on Aging.

She served on the National Advisory Council on Aging for the National Institutes of Health, National Institute on Aging from 2009-2012. In 2010, she received the McDougall Mentoring award which recognizes and honors faculty members who demonstrate an outstanding investment in their mentees’ professional development and success as independent researchers or clinical scientists. In 2014, Dr. LaCroix was elected as a member of the American Epidemiological Society. She has authored more than 300 scientific publications, and was selected as a Thomson Reuters Highly Cited Researcher in 2014.

Susan Reed, MD

Susan Reed, MD, MPH

  • Professor and Division Director, Women's Health, Harborview Medical Center
  • Adjunct Appointment, Epidemiology
  • Program Director, University of Washington Women's Reproductive Health Research Program
  • Affiliate Investigator, Center for Health Studies & Fred Hutchinson Cancer Research Center

Susan Reed MD, MPH, MS is Professor of Obstetrics and Gynecology and Epidemiology, Division Chief at Harborview Medical Center, and Program Director for the National Institutes of Health funded Women’s Reproductive Health Research program at the University of Washington. She has appointments at Fred Hutchinson Cancer Research Center and Group Health Research Institute in Seattle. Her undergraduate and medical degrees are from Stanford, and her masters degrees are from Sarah Lawrence College and University of Washington. She did her residency training at University of California, San Francisco.

Dr. Reed is internationally renowned for her research in midlife women’s health and is recognized nationally for her interest in health disparities among women. She, along with colleagues from Harvard and Group Health, study the relationship of reproductive hormones and mood. She has been principle investigator or co-investigator on over 20 projects, the majority sponsored by the National Institutes of Health. She is currently a principle investigator for the NIH funded network, MsFLASH, performing clinical trials on the treatment of menopausal symptoms, including mood disorders. She has authored over 100 peer-reviewed articles. She is honored with the National Faculty Award in Teaching Excellence from the American College of Obstetrics and Gynecology, several faculty research mentoring awards from the University of Washington, and Best Physician awards for the Seattle area from 2003-present. Dr. Reed and her research team are committed to improving all aspects of physical and mental health care for women, and to reducing existing disparities in the access and provision of this care.