Cancer remains one of the most serious health problems for the US population at the beginning of the 21st century. It is estimated that close to 1.4 million new cancer cases will be diagnosed in 2006, and over one half million persons will die as a consequence. The need for this interdisciplinary training program in cancer epidemiology and biostatistics has never been greater, as there has been a virtual explosion of new knowledge regarding the biological mechanisms underlying the development of cancer, particularly at the molecular level and in regard to the role of genetic determinants. The purpose of our training program is to provide skills in epidemiology and biostatistics that will enable the trainee to address this problem through the conduct of high quality cancer research. The program is housed in the Departments of Epidemiology and Biostatistics in the School of Public Health and Community Medicine of the University of Washington. All of the predoctoral trainees and many of the postdoctoral trainees have been enrolled in the graduate programs that these departments offer. Much of the training also takes place at our affiliated institution, the Fred Hutchinson Cancer Research Center.