Breast Cancer Initiative 2.5 (BCI2.5)



The Breast Cancer Initiative (BCI2.5) is a global campaign to reduce disparities in breast cancer outcomes for 2.5 million women by 2025.

About BCI2.5 

BCI2.5 represents a new commitment to unite the global breast cancer community behind a common goal to make breast health a global priority and reduce disparities in breast cancer outcomes worldwide. The initiative began as a call for action in 2014 supported by the American Cancer Society, Susan G. Komen and the Union for International Cancer Control. Since that initial pledge, BCI2.5 has been engaging partners around the world, assessing need, identifying priorities and defining a strategy to meet this goal. Its consensus-based approach empowers regional champions to bring about change with the aid of BCI2.5 analytic, assessment and planning tools, educational materials and implementation science research methodology. BCI2.5 delivers evidence-based technical expertise and a resource-stratified approach to improving breast health services and care at any resource level. The initiative is inclusive and encourages organizations, institutions and countries to connect and join the effort.

Why BCI2.5?

Breast cancer is the most prevalent cancer in women worldwide. Estimates suggest that 5.8 million women will die from breast cancer by 2025, with a disproportionate number of these deaths occurring in low-resource settings. Higher breast cancer case fatality rates in low-resource settings have been attributed to a lack of awareness regarding the benefits of early detection and treatment, late stage diagnosis and limited access to appropriate care. 

To reduce this global disparity in breast cancer outcomes for 2.5 million women by 2025, BCI2.5 is exploring innovative ways to implement affordable, appropriate, acceptable and feasible evidence-based strategies. A key element of this initiative is identifying, documenting and fostering dissemination of new and innovative approaches to the delivery of breast health care developed in low-resource settings. To achieve this, BCI2.5 collaborates with partners making the best use of available resources to provide technical expertise and promote evidence-based care models for early detection, diagnosis, treatment and supportive care that can be scaled up in LMICs to achieve the goal of reducing disparities in breast cancer outcomes. The initiative pursues an approach that capitalizes on the capabilities of the organizing partners, is aligned with WHO resolutions, addresses the global need and is customized to regions’ unique situations.


Ambassador Sally G. Cowal

”Women in low- and middle-income countries deserve access to the breast cancer early detection and treatment services that could save their lives. It is only in working together with our global colleagues that we can reduce disparities and save the lives we can – and should – be saving. The American Cancer Society is a proud partner in this initiative.”

-Ambassador Sally G. Cowal, Senior Vice President, Global Health, American Cancer Society