Interdisciplinary Training


All peer-reviewed articles resulting from research supported in whole or in part with direct costs from NIH, in this case the T32 (training grant) appointments, must be compliant with the NIH Public Access Policy and must include an acknowledgement of NIH award support, for example: Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under award number T32CA080416.

2018  I  2017  I  2016  I  2015  I  2014  I  2013  I  2012  I  2011  I  2010  I  2009  I  2008


Bender Ignacio RA, Madison AT, Moshiri A, Weiss NS, Mueller BA. A Population-based Study of Perinatal Infection Risk in Women with and without Systemic Lupus Erythematosus and their Infants. Paediatric and perinatal epidemiology. 2018 January;32(1):81-89. doi: 10.1111/ppe.12430. Epub 2017 Dec 1. PubMed PMID: 29194681; PubMed Central PMCID: PMC5771993.

Stewart MD, Zelin E, Dhall A, Walsh T, Upadhyay E, Corn JE, Chatterjee C, King MC, Klevit RE. BARD1 is necessary for ubiquitylation of nucleosomal histone H2A and for transcriptional regulation of estrogen metabolism genes. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1316-1321. doi: 10.1073/pnas.1715467115. Epub 2018 Jan 24. PubMed PMID: 29367421; PubMed Central PMCID: PMC5819413.

Pierce SB, Stewart MD, Gulsuner S, Walsh T, Dhall A, McClellan JM, Klevit RE, King MC. De novo mutation in RING1 with epigenetic effects on neurodevelopment. Proc Natl Acad Sci U S A. 2018 Feb 13;115(7):1558-1563. doi: 10.1073/pnas.1721290115. Epub 2018 Jan 31. PubMed PMID: 29386386; PubMed Central PMCID: PMC5816211.

Ferreccio A, Mathieu J, Detraux D, Somasundaram L, Cavanaugh C, Sopher B, Fischer K, Bello T, M Hussein A, Levy S, Cook S, Sidhu SB, Artoni F, Palpant NJ, Reinecke H, Wang Y, Paddison P, Murry C, Jayadev S, Ware C, Ruohola-Baker H. Inducible CRISPR genome editing platform in naive human embryonic stem cells reveals JARID2 function in self-renewal. Cell Cycle. 2018;17(5):535-549. doi: 10.1080/15384101.2018.1442621. Epub 2018 Apr 5. PubMed PMID: 29466914; PubMed Central PMCID: PMC5969550.

Matreyek KA, Starita LM, Stephany JJ, Martin B, Chiasson MA, Gray VE, Kircher M, Khechaduri A, Dines JN, Hause RJ, Bhatia S, Evans WE, Relling MV, Yang W, Shendure J, Fowler DM. Multiplex assessment of protein variant abundance by massively parallel sequencing. Nature genetics. 2018 June;50(6):874-882. doi: 10.1038/s41588-018-0122-z. Epub 2018 May 21. PubMed PMID: 29785012; PubMed Central PMCID: PMC5980760.

Poudel KR, Roh-Johnson M, Su A, Ho T, Mathsyaraja H, Anderson S, Grady WM, Moens CB, Conacci-Sorrell M, Eisenman RN, Bai J. Competition between TIAM1 and Membranes Balances Endophilin A3 Activity in Cancer Metastasis. Dev Cell. 2018 Jun 18;45(6):738-752.e6. doi: 10.1016/j.devcel.2018.05.021. PubMed PMID: 29920278.

Oseso LN, Chiao EY, Ignacio RAB. Evaluating Antiretroviral Therapy Initiation in HIV-Associated Malignancy: Is There Enough Evidence to Inform Clinical Guidelines? J Natl Compr Canc Netw. 2018 Aug;16(8):927-932. doi: 10.6004/jnccn.2018.7057. PubMed PMID: 30099368.


Driver JW, Geyer EA, Bailey ME, Rice LM, Asbury CL. Direct measurement of conformational strain energy in protofilaments curling outward from disassembling microtubule tips. Elife. 2017 Jun 19;6. pii: e28433. doi: 10.7554/eLife.28433. PubMed PMID: 28628007; PubMed Central PMCID: PMC5515574.

Roh-Johnson M, Shah AN, Stonick JA, Poudel KR, Kargl J, Yang GH, di Martino J, Hernandez RE, Gast CE, Zarour LR, Antoku S, Houghton AM, Bravo-Cordero JJ, Wong MH, Condeelis J, Moens CB. Macrophage-Dependent Cytoplasmic Transfer during Melanoma Invasion In Vivo.Dev Cell. 2017 Dec 4;43(5):549-562.e6. doi: 10.1016/j.devcel.2017.11.003. PubMed PMID: 29207258; PubMed Central PMCID: PMC5728704.

Bell SM, Bedford T. Modern-day SIV viral diversity generated by extensive recombination and cross-species transmission. PLoS Pathog. 2017 Jul 3;13(7):e1006466. doi: 10.1371/journal.ppat.1006466. eCollection 2017 Jul. PubMed PMID: 28672035; PubMed Central PMCID: PMC5510905.

Matreyek KA, Stephany JJ, Fowler DM. A platform for functional assessment of large variant libraries in mammalian cells. Nucleic Acids Res. 2017 Jun 20;45(11):e102. doi: 10.1093/nar/gkx183. PubMed PMID: 28335006; PubMed Central PMCID: PMC5499817.

Sychev ZE, Hu A, DiMaio TA, Gitter A, Camp ND, Noble WS, Wolf-Yadlin A, Lagunoff M. Integrated systems biology analysis of KSHV latent infection reveals viral induction and reliance on peroxisome mediated lipid metabolism. PLoS Pathog. 2017 Mar 3;13(3):e1006256. doi: 10.1371/journal.ppat.1006256. eCollection 2017 Mar. PubMed PMID: 28257516; PubMed Central PMCID: PMC5352148.

Ronen K, Dingens AS, Graham SM, Jaoko W, Mandaliya K, McClelland RS, Overbaugh J. Comprehensive Characterization of Humoral Correlates of Human Immunodeficiency Virus 1 Superinfection Acquisition in High-risk Kenyan Women. EBioMedicine. 2017 Apr;18:216-224. doi: 10.1016/j.ebiom.2017.04.005. Epub 2017 Apr 7. PubMed PMID: 28427948; PubMed Central PMCID: PMC5405187.

Stewart MD, Duncan ED, Coronado E, DaRosa PA, Pruneda JN, Brzovic PS, Klevit RE. Tuning BRCA1 and BARD1 activity to investigate RING ubiquitin ligase mechanisms. Protein Sci. 2017 Mar;26(3):475-483. doi: 10.1002/pro.3091. Epub 2017 Jan 23. PubMed PMID: 27977889; PubMed Central PMCID: PMC5326557.

Bender Ignacio RA, Ramchandani MS, Laing KJ, Johnston CM, Koelle DM. T Cell Immunity to Varicella-Zoster Virus in the Setting of Advanced HIV and Multiple Varicella-Zoster Virus Recurrences. Viral immunology. 2017 January;30(1):77-80. doi: 10.1089/vim.2016.0097. Epub 2016 Nov 21. PubMed PMID: 27870601; PubMed Central PMCID: PMC5220562.


Haddox HK, Dingens AS, Bloom JD. Experimental Estimation of the Effects of All Amino-Acid Mutations to HIV's Envelope Protein on Viral Replication in Cell Culture. PLoS Pathog. 2016 Dec 13;12(12):e1006114. doi: 10.1371/journal.ppat.1006114. eCollection 2016 Dec. PubMed PMID: 27959955; PubMed Central PMCID: PMC5189966.

Ásbjörnsdóttir KH, Hughes JP, Wamalwa D, Langat A, Slyker JA, Okinyi HM, Overbaugh J, Benki-Nugent S, Tapia K, Maleche-Obimbo E, Rowhani-Rahbar A, John-Stewart G. Differences in virologic and immunologic response to antiretroviral therapy among HIV-1-infected infants and children. AIDS. 2016 Nov 28;30(18):2835-2843. PubMed PMID: 27603293; PubMed Central PMCID: PMC5101154.

Dingens AS, Fairfortune TS, Reed S, Mitchell C. Bacterial vaginosis and adverse outcomes among full-term infants: a cohort study. BMC Pregnancy Childbirth. 2016 Sep 22;16(1):278. PubMed PMID: 27658456; PubMed Central PMCID: PMC5034665.

Anderson S, Poudel KR, Roh-Johnson M, Brabletz T, Yu M, Borenstein-Auerbach N, Grady WN, Bai J, Moens CB, Eisenman RN, Conacci-Sorrell M. MYC-nick promotes cell migration by inducing fascin expression and Cdc42 activation. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5481-90. doi: 10.1073/pnas.1610994113. Epub 2016 Aug 26. PubMed PMID: 27566402; PubMed Central PMCID: PMC5027433.

Ásbjörnsdóttir KH, Slyker JA, Maleche-Obimbo E, Wamalwa D, Otieno P, Gichuhi CM, John-Stewart G. Breastfeeding Is Associated with Decreased Risk of Hospitalization among HIV-Exposed, Uninfected Kenyan Infants. J Hum Lact. 2016 Aug;32(3):NP61-6. doi: 10.1177/0890334415607854. Epub 2015 Sep 30. PubMed PMID: 26423513; PubMed Central PMCID: PMC4814344.

Habenicht LM, Albershardt TC, Iritani BM, Ruddell A. Distinct mechanisms of B and T lymphocyte accumulation generate tumor-draining lymph node hypertrophy. Oncoimmunology. 2016 Jun 30;5(8):e1204505. doi: 10.1080/2162402X.2016.1204505. eCollection 2016 Aug. PubMed PMID: 27622075; PubMed Central PMCID: PMC5007965.

Riggle KM, Riehle KJ, Kenerson HL, Turnham R, Homma MK, Kazami M, Samelson B, Bauer R, McKnight GS, Scott JD, Yeung RS. Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma. Pediatr Res. 2016 Jul;80(1):110-8. doi: 10.1038/pr.2016.36. Epub 2016 Mar 8. PubMed PMID: 27027723; PubMed Central PMCID: PMC5105330.

Poudel KR, Dong Y, Yu H, Su A, Ho T, Liu Y, Schulten K, Bai J. A time course of orchestrated endophilin action in sensing, bending, and stabilizing curved membranes. Mol Biol Cell. 2016 Jul 1;27(13):2119-32. doi: 10.1091/mbc.E16-04-0264. Epub 2016 May 11. PubMed PMID: 27170174; PubMed Central PMCID: PMC4927284.

Riggle KM, Turnham R, Scott JD, Yeung RS, Riehle KJ. Fibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From Adult Hepatocellular Carcinoma. Pediatr Blood Cancer. 2016 Jul;63(7):1163-7. doi: 10.1002/pbc.25970. Epub 2016 Mar 14. Review. PubMed PMID: 26990031; PubMed Central PMCID: PMC4877189.

Bender Ignacio RA, Lee JY, Rudek MA, Dittmer DP, Ambinder RF, Krown SE; AIDS Malignancy Consortium (AMC)-059 Study Team.. Brief Report: A Phase 1b/Pharmacokinetic Trial of PTC299, a Novel PostTranscriptional VEGF Inhibitor, for AIDS-Related Kaposi's Sarcoma: AIDS Malignancy Consortium Trial 059. J Acquir Immune Defic Syndr. 2016 May 1;72(1):52-7. doi: 10.1097/QAI.0000000000000918. PubMed PMID: 26689971; PubMed Central PMCID: PMC4838493.

Stewart MD, Ritterhoff T, Klevit RE, Brzovic PS. E2 enzymes: more than just middle men. Cell Res. 2016 Apr;26(4):423-40. doi: 10.1038/cr.2016.35. Epub 2016 Mar 22. Review. PubMed PMID: 27002219; PubMed Central PMCID: PMC4822130.

Turnham RE, Scott JD. Protein kinase A catalytic subunit isoform PRKACA; History, function and physiology. Gene. 2016 Feb 15;577(2):101-8. doi: 10.1016/j.gene.2015.11.052. Epub 2015 Dec 12. Review. PubMed PMID: 26687711; PubMed Central PMCID: PMC4713328.

Jordan-Williams KL, Ramanujam N, Farr AG, Ruddell A. The Lymphatic Endothelial mCLCA1 Antibody Induces Proliferation and Growth of Lymph Node Lymphatic Sinuses. PLoS One. 2016 May 25;11(5):e0156079. doi: 10.1371/journal.pone.0156079. eCollection 2016. PubMed PMID: 27224029; PubMed Central PMCID: PMC4880189.

Bender Ignacio RA, Goldman JD, Magaret AS, Selke S, Huang ML, Gantt S, Johnston C, Phipps WT, Schiffer JT, Zuckerman RA, McClelland RS, Celum C, Corey L, Wald A, Casper C. Patterns of human herpesvirus-8 oral shedding among diverse cohorts of human herpesvirus-8 seropositive persons. Infect Agent Cancer. 2016 Feb 10;11:7. doi: 10.1186/s13027-016-0052-2. eCollection 2016. PubMed PMID: 26865856; PubMed Central PMCID: PMC4748452.


Delbecq SP, Rosenbaum JC, Klevit RE. A Mechanism of Subunit Recruitment in Human Small Heat Shock Protein Oligomers. Biochemistry. 2015 Jul 21;54(28):4276-84. doi: 10.1021/acs.biochem.5b00490. Epub 2015 Jul 7. PubMed PMID: 26098708; PubMed Central PMCID: PMC4512712.

Toledo CM, Ding Y, Hoellerbauer P, Davis RJ, Basom R, Girard EJ, Lee E, Corrin P, Hart T, Bolouri H, Davison J, Zhang Q, Hardcastle J, Aronow BJ, Plaisier CL, Baliga NS, Moffat J, Lin Q, Li XN, Nam DH, Lee J, Pollard SM, Zhu J, Delrow JJ, Clurman BE, Olson JM, Paddison PJ. Genome-wide CRISPR-Cas9 Screens Reveal Loss of Redundancy between PKMYT1 and WEE1 in Glioblastoma Stem-like Cells. Cell Rep. 2015 Dec 22;13(11):2425-39. doi: 10.1016/j.celrep.2015.11.021. Epub 2015 Dec 7. PubMed PMID: 26673326; PubMed Central PMCID: PMC4691575.

Bender Ignacio RA, Perti T, Magaret AS, Rajagopal S, Stevens CE, Huang ML, Selke S, Johnston C, Marrazzo J, Wald A. Oral and Vaginal Tenofovir for Genital Herpes Simplex Virus Type 2 Shedding in Immunocompetent Women: A Double-Blind, Randomized, Cross-over Trial. J Infect Dis. 2015 Dec 15;212(12):1949-56. doi: 10.1093/infdis/jiv317. Epub 2015 Jun 4. PubMed PMID: 26044291; PubMed Central PMCID: PMC4655855.

Mitchell PS, Young JM, Emerman M, Malik HS. Evolutionary Analyses Suggest a Function of MxB Immunity Proteins Beyond Lentivirus Restriction. PLoS Pathog. 2015 Dec 10;11(12):e1005304. doi: 10.1371/journal.ppat.1005304. eCollection 2015 Dec. PubMed PMID: 26658285; PubMed Central PMCID: PMC4687636.

Castelli AA, Rosenthal DG, Bender Ignacio R, Chu HY. Hemophagocytic Lymphohistiocytosis Secondary to Human Immunodeficiency Virus-Associated Histoplasmosis. Open Forum Infect Dis. 2015 Sep 19;2(4):ofv140. doi: 10.1093/ofid/ofv140. eCollection 2015 Dec. PubMed PMID: 26566535; PubMed Central PMCID: PMC4630451.

Williams KL, Cortez V, Dingens AS, Gach JS, Rainwater S, Weis JF, Chen X, Spearman P, Forthal DN, Overbaugh J. HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and Are Commonly Detected in Plasma From HIV-infected humans. EBioMedicine. 2015 Oct;2(10):1464-77. PubMed PMID: 26629541; PubMed Central PMCID: PMC4634620.

Bender Ignacio RA, Koch LL, Dhanireddy S, Charmie Godornes B, Lukehart SA, Marrazzo JM. Syphilis? An Unusual Cause of Surgical Emergency in a Human Immunodeficiency Virus-Infected Man. Open Forum Infect Dis. 2015 Jun 20;2(3):ofv094. doi: 10.1093/ofid/ofv094. eCollection 2015 Sep. PubMed PMID: 26213693; PubMed Central PMCID: PMC4512143.

Vittal V, Stewart MD, Brzovic PS, Klevit RE. Regulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin Ligases. J Biol Chem. 2015 Aug 28;290(35):21244-51. doi: 10.1074/jbc.R115.675165. Epub 2015 Jul 17. Review. PubMed PMID: 26187467; PubMed Central PMCID: PMC4571856.

Ganti SN, Albershardt TC, Iritani BM, Ruddell A. Regulatory B cells preferentially accumulate in tumor-draining lymph nodes and promote tumor growth. Sci Rep. 2015 Jul 20;5:12255. doi: 10.1038/srep12255. PubMed PMID: 26193241; PubMed Central PMCID: PMC4507466.

Klinghoffer RA, Bahrami SB, Hatton BA, Frazier JP, Moreno-Gonzalez A, Strand AD, Kerwin WS, Casalini JR, Thirstrup DJ, You S, Morris SM, Watts KL, Veiseh M, Grenley MO, Tretyak I, Dey J, Carleton M, Beirne E, Pedro KD, Ditzler SH, Girard EJ, Deckwerth TL, Bertout JA, Meleo KA, Filvaroff EH, Chopra R, Press OW, Olson JM. A technology platform to assess multiple cancer agents simultaneously within a patient's tumor. Sci Transl Med. 2015 Apr 22;7(284):284ra58. doi: 10.1126/scitranslmed.aaa7489. PubMed PMID: 25904742; PubMed Central PMCID: PMC4770902.

DeBerg HA, Bankston JR, Rosenbaum JC, Brzovic PS, Zagotta WN, Stoll S. Structural mechanism for the regulation of HCN ion channels by the accessory protein TRIP8b. Structure. 2015 Apr 7;23(4):734-44. doi: 10.1016/j.str.2015.02.007. Epub 2015 Mar 19. PubMed PMID: 25800552; PubMed Central PMCID: PMC4394039.

Mirus JE, Zhang Y, Li CI, Lokshin AE, Prentice RL, Hingorani SR, Lampe PD. Cross-species antibody microarray interrogation identifies a 3-protein panel of plasma biomarkers for early diagnosis of pancreas cancer. Clin Cancer Res. 2015 Apr 1;21(7):1764-71. doi: 10.1158/1078-0432.CCR-13-3474. Epub 2015 Jan 14. PubMed PMID: 25589628; PubMed Central PMCID: PMC4391639.

Cortez V, Wang B, Dingens A, Chen MM, Ronen K, Georgiev IS, McClelland RS, Overbaugh J. The Broad Neutralizing Antibody Responses after HIV-1 Superinfection Are Not Dominated by Antibodies Directed to Epitopes Common in Single Infection. PLoS Pathog. 2015 Jul 9;11(7):e1004973. doi: 10.1371/journal.ppat.1002611. Epub 2012 Mar 29. PubMed PMID: 22479183; PubMed Central PMCID: PMC3315492.

Bender Ignacio RA, Koch LL, Dhanireddy S, Charmie Godornes B, Lukehart SA, Marrazzo JM. Syphilis? An Unusual Cause of Surgical Emergency in a Human Immunodeficiency Virus-Infected Man. Open Forum Infect Dis. 2015 Jun 20;2(3):ofv094. doi: 10.1093/ofid/ofv094. eCollection 2015 Sep. PubMed PMID: 26213693; PubMed Central PMCID: PMC4512143.

Castelli AA, Rosenthal DG, Bender Ignacio R, Chu HY. Hemophagocytic Lymphohistiocytosis Secondary to Human Immunodeficiency Virus-Associated Histoplasmosis. Open Forum Infect Dis. 2015 Sep 19;2(4):ofv140. doi: 10.1093/ofid/ofv140. eCollection 2015 Dec. PubMed PMID: 26566535; PubMed Central PMCID: PMC4630451.

Williams KL, Cortez V, Dingens AS, Gach JS, Rainwater S, Weis JF, Chen X, Spearman P, Forthal DN, Overbaugh J. HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and Are Commonly Detected in Plasma From HIV-infected humans. EBioMedicine. 2015 Oct;2(10):1464-77. PubMed PMID: 26629541; PubMed Central PMCID: PMC4634620.


Weber ND, Stone D, Sedlak RH, De Silva Feelixge HS, Roychoudhury P, Schiffer JT, Aubert M, Jerome KR. AAV-mediated delivery of zinc finger nucleases targeting hepatitis B virus inhibits active replication. PLoS One. 2014 May 14;9(5):e97579. doi: 10.1371/journal.pone.0097579. eCollection 2014. PubMed PMID: 24827459; PubMed Central PMCID: PMC4020843.

Mirus JE, Zhang Y, Hollingsworth MA, Solan JL, Lampe PD, Hingorani SR. Spatiotemporal proteomic analyses during pancreas cancer progression identifies serine/threonine stress kinase 4 (STK4) as a novel candidate biomarker for early stage disease. Mol Cell Proteomics. 2014 Dec;13(12):3484-96. doi: 10.1074/mcp.M113.036517. Epub 2014 Sep 15. PubMed PMID: 25225358; PubMed Central PMCID: PMC4256499.

Paulson KG, Tegeder A, Willmes C, Iyer JG, Afanasiev OK, Schrama D, Koba S, Thibodeau R, Nagase K, Simonson WT, Seo A, Koelle DM, Madeleine M, Bhatia S, Nakajima H, Sano S, Hardwick JS, Disis ML, Cleary MA, Becker JC, Nghiem P. Downregulation of MHC-I expression is prevalent but reversible in Merkel cell carcinoma. Cancer Immunol Res. 2014 Nov;2(11):1071-9. doi: 10.1158/2326-6066.CIR-14-0005. Epub 2014 Aug 12. PubMed PMID: 25116754; PubMed Central PMCID: PMC4221542.

London N, Biggins S. Signalling dynamics in the spindle checkpoint response. Nat Rev Mol Cell Biol. 2014 Nov;15(11):736-47. doi: 10.1038/nrm3888. Epub 2014 Oct 10. Review. PubMed PMID: 25303117; PubMed Central PMCID: PMC4283840.

Chevillet JR, Kang Q, Ruf IK, Briggs HA, Vojtech LN, Hughes SM, Cheng HH, Arroyo JD, Meredith EK, Gallichotte EN, Pogosova-Agadjanyan EL, Morrissey C, Stirewalt DL, Hladik F, Yu EY, Higano CS, Tewari M. Quantitative and stoichiometric analysis of the microRNA content of exosomes. Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14888-93. doi: 10.1073/pnas.1408301111. Epub 2014 Sep 29. PubMed PMID: 25267620; PubMed Central PMCID: PMC4205618.

Vojtech L, Woo S, Hughes S, Levy C, Ballweber L, Sauteraud RP, Strobl J, Westerberg K, Gottardo R, Tewari M, Hladik F. Exosomes in human semen carry a distinctive repertoire of small non-coding RNAs with potential regulatory functions. Nucleic Acids Res. 2014 Jun;42(11):7290-304. doi: 10.1093/nar/gku347. Epub 2014 May 16. PubMed PMID: 24838567; PubMed Central PMCID: PMC4066774.

Yao Z, Macquarrie KL, Fong AP, Tapscott SJ, Ruzzo WL, Gentleman RC. Discriminative motif analysis of high-throughput dataset. Bioinformatics. 2014 Mar 15;30(6):775-83. doi: 10.1093/bioinformatics/btt615. Epub 2013 Oct 25. PubMed PMID: 24162561; PubMed Central PMCID: PMC3957073.

Correia BE, Bates JT, Loomis RJ, Baneyx G, Carrico C, Jardine JG, Rupert P, Correnti C, Kalyuzhniy O, Vittal V, Connell MJ, Stevens E, Schroeter A, Chen M, Macpherson S, Serra AM, Adachi Y, Holmes MA, Li Y, Klevit RE, Graham BS, Wyatt RT, Baker D, Strong RK, Crowe JE Jr, Johnson PR, Schief WR. Proof of principle for epitope-focused vaccine design. Nature. 2014 Mar 13;507(7491):201-6. doi: 10.1038/nature12966. Epub 2014 Feb 5. PubMed PMID: 24499818; PubMed Central PMCID: PMC4260937.

Lauper JM, Monnat RJ Jr. Diabetes mellitus and cancer in Werner syndrome. Acta Diabetol. 2014 Feb;51(1):159-61. doi: 10.1007/s00592-013-0456-z. Epub 2013 Feb 6. PubMed PMID: 23386316; PubMed Central PMCID: PMC3669637.

Slyker J, Farquhar C, Atkinson C, Ásbjörnsdóttir K, Roxby A, Drake A, Kiarie J, Wald A, Boeckh M, Richardson B, Odem-Davis K, John-Stewart G, Emery V. Compartmentalized cytomegalovirus replication and transmission in the setting of maternal HIV-1 infection. Clin Infect Dis. 2014 Feb;58(4):564-72. doi: 10.1093/cid/cit727. Epub 2013 Nov 5. PubMed PMID: 24192386; PubMed Central PMCID: PMC3905754.

London N, Biggins S. Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint. Genes Dev. 2014 Jan 15;28(2):140-52. doi: 10.1101/gad.233700.113. Epub 2014 Jan 8. PubMed PMID: 24402315; PubMed Central PMCID: PMC3909788.

Roxby AC, Atkinson C, Asbjörnsdóttir K, Farquhar C, Kiarie JN, Drake AL, Wald A, Boeckh M, Richardson B, Emery V, John-Stewart G, Slyker JA. Maternal valacyclovir and infant cytomegalovirus acquisition: a randomized controlled trial among HIV-infected women. PLoS One. 2014 Feb 4;9(2):e87855. doi: 10.1371/journal.pone.0087855. eCollection 2014. PubMed PMID: 24504006; PubMed Central PMCID: PMC3913686.

Jordan-Williams KL, Ruddell A. Culturing purifies murine lymph node lymphatic endothelium. Lymphat Res Biol. 2014 Sep;12(3):144-9. doi: 10.1089/lrb.2013.0053. Epub 2014 May 16. PubMed PMID: 24837301; PubMed Central PMCID: PMC4171392.


McGoldrick SM, Bleakley ME, Guerrero A, Turtle CJ, Yamamoto TN, Pereira SE, Delaney CS, Riddell SR. Cytomegalovirus-specific T cells are primed early after cord blood transplant but fail to control virus in vivo. Blood. 2013 Apr 4;121(14):2796-803. doi: 10.1182/blood-2012-09-453720. Epub 2013 Feb 14. PubMed PMID: 23412093; PubMed Central PMCID: PMC3617639.

Schiffer JT, Corey L. Rapid host immune response and viral dynamics in herpes simplex virus-2 infection. Nat Med. 2013 Mar;19(3):280-90. doi: 10.1038/nm.3103. PubMed PMID: 23467247; PubMed Central PMCID: PMC3981536.

Schiffer JT, Swan D, Al Sallaq R, Magaret A, Johnston C, Mark KE, Selke S, Ocbamichael N, Kuntz S, Zhu J, Robinson B, Huang ML, Jerome KR, Wald A, Corey L. Rapid localized spread and immunologic containment define Herpes simplex virus-2 reactivation in the human genital tract. Elife. 2013 Apr 16;2:e00288. doi: 10.7554/eLife.00288. PubMed PMID: 23606943; PubMed Central PMCID: PMC3629793.

Welcker M, Larimore EA, Swanger J, Bengoechea-Alonso MT, Grim JE, Ericsson J, Zheng N, Clurman BE. Fbw7 dimerization determines the specificity and robustness of substrate degradation. Genes Dev. 2013 Dec 1;27(23):2531-6. doi: 10.1101/gad.229195.113. PubMed PMID: 24298052; PubMed Central PMCID: PMC3861666.

Carlson AE, Rosenbaum JC, Brelidze TI, Klevit RE, Zagotta WN. Flavonoid regulation of HCN2 channels. J Biol Chem. 2013 Nov 15;288(46):33136-45. doi: 10.1074/jbc.M113.501759. Epub 2013 Oct 1. PubMed PMID: 24085296; PubMed Central PMCID: PMC3831264.

Ásbjörnsdóttir KH, Slyker JA, Weiss NS, Mbori-Ngacha D, Maleche-Obimbo E, Wamalwa D, John-Stewart G. Breastfeeding is associated with decreased pneumonia incidence among HIV-exposed, uninfected Kenyan infants. AIDS. 2013 Nov 13;27(17):2809-15. doi: 10.1097/01.aids.0000432540.59786.6d. PubMed PMID: 23921609; PubMed Central PMCID: PMC4084504.

Bierle CJ, Semmens KM, Geballe AP. Double-stranded RNA binding by the human cytomegalovirus PKR antagonist TRS1. Virology. 2013 Jul 20;442(1):28-37. doi: 10.1016/j.virol.2013.03.024. Epub 2013 Apr 17. PubMed PMID: 23601785; PubMed Central PMCID: PMC3782281.

Jardine J, Julien JP, Menis S, Ota T, Kalyuzhniy O, McGuire A, Sok D, Huang PS, MacPherson S, Jones M, Nieusma T, Mathison J, Baker D, Ward AB, Burton DR, Stamatatos L, Nemazee D, Wilson IA, Schief WR. Rational HIV immunogen design to target specific germline B cell receptors. Science. 2013 May 10;340(6133):711-6. doi: 10.1126/science.1234150. Epub 2013 Mar 28. PubMed PMID: 23539181; PubMed Central PMCID: PMC3689846.

Hubert CG, Bradley RK, Ding Y, Toledo CM, Herman J, Skutt-Kakaria K, Girard EJ, Davison J, Berndt J, Corrin P, Hardcastle J, Basom R, Delrow JJ, Webb T, Pollard SM, Lee J, Olson JM, Paddison PJ. Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A. Genes Dev. 2013 May 1;27(9):1032-45. doi: 10.1101/gad.212548.112. PubMed PMID: 23651857; PubMed Central PMCID: PMC3656321.

McGuire AT, Hoot S, Dreyer AM, Lippy A, Stuart A, Cohen KW, Jardine J, Menis S, Scheid JF, West AP, Schief WR, Stamatatos L. Engineering HIV envelope protein to activate germline B cell receptors of broadly neutralizing anti-CD4 binding site antibodies. J Exp Med. 2013 Apr 8;210(4):655-63. doi: 10.1084/jem.20122824. Epub 2013 Mar 25. PubMed PMID: 23530120; PubMed Central PMCID: PMC3620356.

Pierce NW, Lee JE, Liu X, Sweredoski MJ, Graham RL, Larimore EA, Rome M, Zheng N, Clurman BE, Hess S, Shan SO, Deshaies RJ. Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins. Cell. 2013 Mar 28;153(1):206-15. doi: 10.1016/j.cell.2013.02.024. Epub 2013 Feb 28. PubMed PMID: 23453757; PubMed Central PMCID: PMC3656483.

Malfavon-Borja R, Wu LI, Emerman M, Malik HS. Birth, decay, and reconstruction of an ancient TRIMCyp gene fusion in primate genomes. Proc Natl Acad Sci U S A. 2013 Feb 12;110(7):E583-92. doi: 10.1073/pnas.1216542110. Epub 2013 Jan 14. PubMed PMID: 23319649; PubMed Central PMCID: PMC3574956.

Ding Y, Hubert CG, Herman J, Corrin P, Toledo CM, Skutt-Kakaria K, Vazquez J, Basom R, Zhang B, Risler JK, Pollard SM, Nam DH, Delrow JJ, Zhu J, Lee J, DeLuca J, Olson JM, Paddison PJ. Cancer-Specific requirement for BUB1B/BUBR1 in human brain tumor isolates and genetically transformed cells. Cancer Discov. 2013 Feb;3(2):198-211. doi: 10.1158/2159-8290.CD-12-0353. Epub 2012 Nov 15. PubMed PMID: 23154965; PubMed Central PMCID: PMC3632446.

MacQuarrie KL, Yao Z, Fong AP, Diede SJ, Rudzinski ER, Hawkins DS, Tapscott SJ. Comparison of genome-wide binding of MyoD in normal human myogenic cells and rhabdomyosarcomas identifies regional and local suppression of promyogenic transcription factors. Mol Cell Biol. 2013 Feb;33(4):773-84. doi: 10.1128/MCB.00916-12. Epub 2012 Dec 10. PubMed PMID: 23230269; PubMed Central PMCID: PMC3571334.

Davis MA, Larimore EA, Fissel BM, Swanger J, Taatjes DJ, Clurman BE. The SCF-Fbw7 ubiquitin ligase degrades MED13 and MED13L and regulates CDK8 module association with Mediator.Genes Dev. 2013 Jan 15;27(2):151-6. doi: 10.1101/gad.207720.112. Epub 2013 Jan 15. PubMed PMID: 23322298; PubMed Central PMCID: PMC3566307.

Poulton EJ, Levy L, Lampe JW, Shen DD, Tracy J, Shuhart MC, Thummel KE, Eaton DL. Sulforaphane is not an effective antagonist of the human pregnane X-receptor in vivo. Toxicol Appl Pharmacol. 2013 Jan 1;266(1):122-31. doi: 10.1016/j.taap.2012.10.029. Epub 2012 Nov 12. PubMed PMID: 23153560; PubMed Central PMCID: PMC3538144.

Lauper JM, Krause A, Vaughan TL, Monnat RJ Jr. Spectrum and risk of neoplasia in Werner syndrome: a systematic review. PLoS One. 2013;8(4):e59709. doi: 10.1371/journal.pone.0059709. Epub 2013 Apr 1. Review. PubMed PMID: 23573208; PubMed Central PMCID: PMC3613408.

Malfavon-Borja R, Sawyer SL, Wu LI, Emerman M, Malik HS. An evolutionary screen highlights canonical and noncanonical candidate antiviral genes within the primate TRIM gene family.Genome Biol Evol. 2013;5(11):2141-54. doi: 10.1093/gbe/evt163. PubMed PMID: 24158625; PubMed Central PMCID: PMC3845644.

Manion MK, Hockenbery DM. Targeting BCL-2-related proteins in cancer therapy. Cancer Biol Ther. 2003 Jul-Aug;2(4 Suppl 1):S105-14. PubMed PMID: 14508087.


Guerrero A, Riddell SR, Storek J, Stevens-Ayers T, Storer B, Zaia JA, Forman S, Negrin RS, Chauncey T, Bensinger W, Boeckh M. Cytomegalovirus viral load and virus-specific immune reconstitution after peripheral blood stem cell versus bone marrow transplantation. Biol Blood Marrow Transplant. 2012 Jan;18(1):66-75. doi: 10.1016/j.bbmt.2011.05.010. Epub 2011 May 20. PubMed PMID: 21664286; PubMed Central PMCID: PMC3237869.

Johnston C, Saracino M, Kuntz S, Magaret A, Selke S, Huang ML, Schiffer JT, Koelle DM, Corey L, Wald A. Standard-dose and high-dose daily antiviral therapy for short episodes of genital HSV-2 reactivation: three randomised, open-label, cross-over trials. Lancet. 2012 Feb 18;379(9816):641-7. doi: 10.1016/S0140-6736(11)61750-9. Epub 2012 Jan 4. Erratum in: Lancet. 2012 Feb 18;379(9816):616. PubMed PMID: 22225814; PubMed Central PMCID: PMC3420069.

Schouten JT, Schiffer JTEqual HIV-1 decay kinetics in HSV-2-infected and HSV-2-uninfected clinical trial participants treated with antiretroviral therapy. J Acquir Immune Defic Syndr. 2012 May 1;60(1):68-71. doi: 10.1097/QAI.0b013e31824bed3f. PubMed PMID: 22330608; PubMed Central PMCID: PMC3331968.

Moss NJ, Magaret A, Laing KJ, Kask AS, Wang M, Mark KE, Schiffer JT, Wald A, Koelle DM. Peripheral blood CD4 T-cell and plasmacytoid dendritic cell (pDC) reactivity to herpes simplex virus 2 and pDC number do not correlate with the clinical or virologic severity of recurrent genital herpes. J Virol. 2012 Sep;86(18):9952-63. doi: 10.1128/JVI.00829-12. Epub 2012 Jul 3. PubMed PMID: 22761381; PubMed Central PMCID: PMC3446596.

Ota T, Doyle-Cooper C, Cooper AB, Huber M, Falkowska E, Doores KJ, Hangartner L, Le K, Sok D, Jardine J, Lifson J, Wu X, Mascola JR, Poignard P, Binley JM, Chakrabarti BK, Schief WR, Wyatt RT, Burton DR, Nemazee D. Anti-HIV B Cell lines as candidate vaccine biosensors. J Immunol. 2012 Nov 15;189(10):4816-24. doi: 10.4049/jimmunol.1202165. Epub 2012 Oct 12. PubMed PMID: 23066156; PubMed Central PMCID: PMC3626558.

White TA, Kwon EM, Fu R, Lucas JM, Ostrander EA, Stanford JL, Nelson PS. The monoamine oxidase A gene promoter repeat and prostate cancer risk. Prostate. 2012 Nov;72(15):1622-7. doi: 10.1002/pros.22515. Epub 2012 Apr 2. PubMed PMID: 22473857; PubMed Central PMCID: PMC3532925.

Albershardt TC, Iritani BM, Ruddell A. Evaluation of reference genes for quantitative PCR analysis of mouse lymphocytes. J Immunol Methods. 2012 Oct 31;384(1-2):196-9. doi: 10.1016/j.jim.2012.07.020. Epub 2012 Aug 4. PubMed PMID: 22884776; PubMed Central PMCID: PMC3432750.

Schiffer JT, Aubert M, Weber ND, Mintzer E, Stone D, Jerome KR. Targeted DNA mutagenesis for the cure of chronic viral infections. J Virol. 2012 Sep;86(17):8920-36. doi: 10.1128/JVI.00052-12. Epub 2012 Jun 20. Review. PubMed PMID: 22718830; PubMed Central PMCID: PMC3416169.

Rajapakse I, Perlman MD, Martin PJ, Hansen JA, Kooperberg C. Multivariate detection of gene-gene interactions. Genet Epidemiol. 2012 Sep;36(6):622-30. doi: 10.1002/gepi.21656. Epub 2012 Jul 10. PubMed PMID: 22782518; PubMed Central PMCID: PMC3556521.

Li CI, Mirus JE, Zhang Y, Ramirez AB, Ladd JJ, Prentice RL, McIntosh MW, Hanash SM, Lampe PD. Discovery and preliminary confirmation of novel early detection biomarkers for triple-negative breast cancer using preclinical plasma samples from the Women's Health Initiative observational study. Breast Cancer Res Treat. 2012 Sep;135(2):611-8. doi: 10.1007/s10549-012-2204-4. Epub 2012 Aug 19. PubMed PMID: 22903690; PubMed Central PMCID: PMC3439142.

Reed JC, Molter B, Geary CD, McNevin J, McElrath J, Giri S, Klein KC, Lingappa JR. HIV-1 Gag co-opts a cellular complex containing DDX6, a helicase that facilitates capsid assembly. J Cell Biol. 2012 Aug 6;198(3):439-56. doi: 10.1083/jcb.201111012. Epub 2012 Jul 30. PubMed PMID: 22851315; PubMed Central PMCID: PMC3413349.

Márquez-Rosado L, Solan JL, Dunn CA, Norris RP, Lampe PD. Connexin43 phosphorylation in brain, cardiac, endothelial and epithelial tissues. Biochim Biophys Acta. 2012 Aug;1818(8):1985-92. doi: 10.1016/j.bbamem.2011.07.028. Epub 2011 Jul 26. Review. PubMed PMID: 21819962; PubMed Central PMCID: PMC3241956.

Bailey-Wilson JE, Childs EJ, Cropp CD, Schaid DJ, Xu J, Camp NJ, Cannon-Albright LA, Farnham JM, George A, Powell I, Carpten JD, Giles GG, Hopper JL, Severi G, English DR, Foulkes WD, Mæhle L, Møller P, Eeles R, Easton D, Guy M, Edwards S, Badzioch MD, Whittemore AS, Oakley-Girvan I, Hsieh CL, Dimitrov L, Stanford JL, Karyadi DM, Deutsch K, McIntosh L, Ostrander EA, Wiley KE, Isaacs SD, Walsh PC, Thibodeau SN, McDonnell SK, Hebbring S, Lange EM, Cooney KA, Tammela TL, Schleutker J, Maier C, Bochum S, Hoegel J, Grönberg H, Wiklund F, Emanuelsson M, Cancel-Tassin G, Valeri A, Cussenot O, Isaacs WB; International Consortium for Prostate Cancer Genetics.. Analysis of Xq27-28 linkage in the international consortium for prostate cancer genetics (ICPCG) families. BMC Med Genet. 2012 Jun 19;13:46. doi: 10.1186/1471-2350-13-46. PubMed PMID: 22712434; PubMed Central PMCID: PMC3495053.

Provine NM, Cortez V, Chohan V, Overbaugh J. The neutralization sensitivity of viruses representing human immunodeficiency virus type 1 variants of diverse subtypes from early in infection is dependent on producer cell, as well as characteristics of the specific antibody and envelope variant. Virology. 2012 May 25;427(1):25-33. doi: 10.1016/j.virol.2012.02.001. Epub 2012 Feb 25. PubMed PMID: 22369748; PubMed Central PMCID: PMC3321740.

London N, Ceto S, Ranish JA, Biggins S. Phosphoregulation of Spc105 by Mps1 and PP1 regulates Bub1 localization to kinetochores. Curr Biol. 2012 May 22;22(10):900-6. doi: 10.1016/j.cub.2012.03.052. Epub 2012 Apr 19. PubMed PMID: 22521787; PubMed Central PMCID: PMC3723133.

Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, Theurillat JP, White TA, Stojanov P, Van Allen E, Stransky N, Nickerson E, Chae SS, Boysen G, Auclair D, Onofrio RC, Park K, Kitabayashi N, MacDonald TY, Sheikh K, Vuong T, Guiducci C, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Hussain WM, Ramos AH, Winckler W, Redman MC, Ardlie K, Tewari AK, Mosquera JM, Rupp N, Wild PJ, Moch H, Morrissey C, Nelson PS, Kantoff PW, Gabriel SB, Golub TR, Meyerson M, Lander ES, Getz G, Rubin MA, Garraway LA. Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. Nat Genet. 2012 May 20;44(6):685-9. doi: 10.1038/ng.2279. PubMed PMID: 22610119; PubMed Central PMCID: PMC3673022.

Fong AP, Yao Z, Zhong JW, Cao Y, Ruzzo WL, Gentleman RC, Tapscott SJ. Genetic and epigenetic determinants of neurogenesis and myogenesis. Dev Cell. 2012 Apr 17;22(4):721-35. doi: 10.1016/j.devcel.2012.01.015. Epub 2012 Mar 22. PubMed PMID: 22445365; PubMed Central PMCID: PMC3331915.

Mahoney SE, Yao Z, Keyes CC, Tapscott SJ, Diede SJ. Genome-wide DNA methylation studies suggest distinct DNA methylation patterns in pediatric embryonal and alveolar rhabdomyosarcomas. Epigenetics. 2012 Apr;7(4):400-8. doi: 10.4161/epi.19463. Epub 2012 Apr 1. PubMed PMID: 22419069; PubMed Central PMCID: PMC3368822.

Li H, Ulge UY, Hovde BT, Doyle LA, Monnat RJ Jr. Comprehensive homing endonuclease target site specificity profiling reveals evolutionary constraints and enables genome engineering applications. Nucleic Acids Res. 2012 Mar;40(6):2587-98. doi: 10.1093/nar/gkr1072. Epub 2011 Nov 25. PubMed PMID: 22121229; PubMed Central PMCID: PMC3315327.

Guenthoer J, Diede SJ, Tanaka H, Chai X, Hsu L, Tapscott SJ, Porter PL. Assessment of palindromes as platforms for DNA amplification in breast cancer. Genome Res. 2012 Feb;22(2):232-45. doi: 10.1101/gr.117226.110. Epub 2011 Jul 13. PubMed PMID: 21752925; PubMed Central PMCID: PMC3266031.

Vaughan AE, Mendoza R, Aranda R, Battini JL, Miller AD. Xpr1 is an atypical G-protein-coupled receptor that mediates xenotropic and polytropic murine retrovirus neurotoxicity. J Virol. 2012 Feb;86(3):1661-9. doi: 10.1128/JVI.06073-11. Epub 2011 Nov 16. PubMed PMID: 22090134; PubMed Central PMCID: PMC3264382.

Knouf EC, Garg K, Arroyo JD, Correa Y, Sarkar D, Parkin RK, Wurz K, O'Briant KC, Godwin AK, Urban ND, Ruzzo WL, Gentleman R, Drescher CW, Swisher EM, Tewari M. An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription.Nucleic Acids Res. 2012 Jan;40(2):499-510. doi: 10.1093/nar/gkr731. Epub 2011 Sep 14. PubMed PMID: 21917857; PubMed Central PMCID: PMC3258134.

Jaworski JP, Krebs SJ, Trovato M, Kovarik DN, Brower Z, Sutton WF, Waagmeester G, Sartorius R, D'Apice L, Caivano A, Doria-Rose NA, Malherbe D, Montefiori DC, Barnett S, De Berardinis P, Haigwood NL. Co-immunization with multimeric scaffolds and DNA rapidly induces potent autologous HIV-1 neutralizing antibodies and CD8+ T cells. PLoS One. 2012;7(2):e31464. doi: 10.1371/journal.pone.0031464. Epub 2012 Feb 16. PubMed PMID: 22359593; PubMed Central PMCID: PMC3281069.

Cortez V, Odem-Davis K, McClelland RS, Jaoko W, Overbaugh J. HIV-1 superinfection in women broadens and strengthens the neutralizing antibody response. PLoS Pathog. 2012;8(3):e1002611. doi: 10.1371/journal.ppat.1002611. Epub 2012 Mar 29. PubMed PMID: 22479183; PubMed Central PMCID: PMC3315492.

Mendoza R, Silverman RH, Klein EA, Miller AD. No biological evidence of XMRV in blood or prostatic fluid from prostate cancer patients. PLoS One. 2012;7(5):e36073. doi: 10.1371/journal.pone.0036073. Epub 2012 May 16. PubMed PMID: 22615749; PubMed Central PMCID: PMC3353987.

Koba S, Paulson KG, Nagase K, Tegeder A, Thibodeau R, Iyer JG, Narisawa Y, Nghiem P. Diagnostic biopsy does not commonly induce intratumoral CD8 T cell infiltration in Merkel cell carcinoma. PLoS One. 2012;7(7):e41465. doi: 10.1371/journal.pone.0041465. Epub 2012 Jul 31. PubMed PMID: 22859987; PubMed Central PMCID: PMC3409202.


Schiffer JT, Wald A, Selke S, Corey L, Magaret A. The kinetics of mucosal herpes simplex virus-2 infection in humans: evidence for rapid viral-host interactions. J Infect Dis. 2011 Aug 15;204(4):554-61. doi: 10.1093/infdis/jir314. PubMed PMID: 21791657; PubMed Central PMCID: PMC3144170.

Schiffer JT, Magaret A, Selke S, Corey L, Wald A. Detailed analysis of mucosal herpes simplex virus-2 replication kinetics with and without antiviral therapy. J Antimicrob Chemother. 2011 Nov;66(11):2593-600. doi: 10.1093/jac/dkr346. Epub 2011 Aug 24. PubMed PMID: 21865349; PubMed Central PMCID: PMC3191945.

Brzovic PS, Heikaus CC, Kisselev L, Vernon R, Herbig E, Pacheco D, Warfield L, Littlefield P, Baker D, Klevit RE, Hahn S. The acidic transcription activator Gcn4 binds the mediator subunit Gal11/Med15 using a simple protein interface forming a fuzzy complex. Mol Cell. 2011 Dec 23;44(6):942-53. doi: 10.1016/j.molcel.2011.11.008. PubMed PMID: 22195967; PubMed Central PMCID: PMC3246216.

Lovelace E, Xu H, Blish CA, Strong R, Overbaugh J. The role of amino acid changes in the human immunodeficiency virus type 1 transmembrane domain in antibody binding and neutralization. Virology. 2011 Dec 20;421(2):235-44. doi: 10.1016/j.virol.2011.09.032. Epub 2011 Oct 24. PubMed PMID: 22029936; PubMed Central PMCID: PMC3249416.

Lee S, Paulson KG, Murchison EP, Afanasiev OK, Alkan C, Leonard JH, Byrd DR, Hannon GJ, Nghiem P. Identification and validation of a novel mature microRNA encoded by the Merkel cell polyomavirus in human Merkel cell carcinomas. J Clin Virol. 2011 Nov;52(3):272-5. doi: 10.1016/j.jcv.2011.08.012. Epub 2011 Sep 9. PubMed PMID: 21907614; PubMed Central PMCID: PMC3196837.

Kumar A, White TA, MacKenzie AP, Clegg N, Lee C, Dumpit RF, Coleman I, Ng SB, Salipante SJ, Rieder MJ, Nickerson DA, Corey E, Lange PH, Morrissey C, Vessella RL, Nelson PS, Shendure J. Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers. Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17087-92. doi: 10.1073/pnas.1108745108. Epub 2011 Sep 26. PubMed PMID: 21949389; PubMed Central PMCID: PMC3193229.

Mendoza R, Vaughan AE, Miller AD. The left half of the XMRV retrovirus is present in an endogenous retrovirus of NIH/3T3 Swiss mouse cells. J Virol. 2011 Sep;85(17):9247-8. doi: 10.1128/JVI.05137-11. Epub 2011 Jun 22. PubMed PMID: 21697491; PubMed Central PMCID: PMC3165791.

Klein KC, Reed JC, Tanaka M, Nguyen VT, Giri S, Lingappa JR. HIV Gag-leucine zipper chimeras form ABCE1-containing intermediates and RNase-resistant immature capsids similar to those formed by wild-type HIV-1 Gag. J Virol. 2011 Jul;85(14):7419-35. doi: 10.1128/JVI.00288-11. Epub 2011 May 4. PubMed PMID: 21543480; PubMed Central PMCID: PMC3126549.

Conerly ML, MacQuarrie KL, Fong AP, Yao Z, Tapscott SJ. Polycomb-mediated repression during terminal differentiation: what don't you want to be when you grow up? Genes Dev. 2011 May 15;25(10):997-1003. doi: 10.1101/gad.2054311. PubMed PMID: 21576260; PubMed Central PMCID: PMC3093125.

Windbichler N, Menichelli M, Papathanos PA, Thyme SB, Li H, Ulge UY, Hovde BT, Baker D, Monnat RJ Jr, Burt A, Crisanti A. A synthetic homing endonuclease-based gene drive system in the human malaria mosquito. Nature. 2011 May 12;473(7346):212-5. doi: 10.1038/nature09937. Epub 2011 Apr 20. PubMed PMID: 21508956; PubMed Central PMCID: PMC3093433.

Ulge UY, Baker DA, Monnat RJ Jr. Comprehensive computational design of mCreI homing endonuclease cleavage specificity for genome engineering. Nucleic Acids Res. 2011 May;39(10):4330-9. doi: 10.1093/nar/gkr022. Epub 2011 Feb 1. PubMed PMID: 21288879; PubMed Central PMCID: PMC3105429.

Paulson KG, Iyer JG, Tegeder AR, Thibodeau R, Schelter J, Koba S, Schrama D, Simonson WT, Lemos BD, Byrd DR, Koelle DM, Galloway DA, Leonard JH, Madeleine MM, Argenyi ZB, Disis ML, Becker JC, Cleary MA, Nghiem P. Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival. J Clin Oncol. 2011 Apr 20;29(12):1539-46. doi: 10.1200/JCO.2010.30.6308. Epub 2011 Mar 21. PubMed PMID: 21422430; PubMed Central PMCID: PMC3082974.

Welcker M, Larimore EA, Frappier L, Clurman BE. Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3. Mol Cell Biol. 2011 Mar;31(6):1214-24. doi: 10.1128/MCB.01347-10. Epub 2011 Jan 10. PubMed PMID: 21220517; PubMed Central PMCID: PMC3067902.

Yager JE, Kadiyala S, Weiser SD. HIV/AIDS, food supplementation and livelihood programs in Uganda: a way forward? PLoS One. 2011;6(10):e26117. doi: 10.1371/journal.pone.0026117. Epub 2011 Oct 12. PubMed PMID: 22022530; PubMed Central PMCID: PMC3192151.

Gianakopoulos PJ, Mehta V, Voronova A, Cao Y, Yao Z, Coutu J, Wang X, Waddington MS, Tapscott SJ, Skerjanc IS. MyoD directly up-regulates premyogenic mesoderm factors during induction of skeletal myogenesis in stem cells. J Biol Chem. 2011 Jan 28;286(4):2517-25. doi: 10.1074/jbc.M110.163709. Epub 2010 Nov 15. PubMed PMID: 21078671; PubMed Central PMCID: PMC3024746.

Palii CG, Perez-Iratxeta C, Yao Z, Cao Y, Dai F, Davison J, Atkins H, Allan D, Dilworth FJ, Gentleman R, Tapscott SJ, Brand M. Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages. EMBO J. 2011 Feb 2;30(3):494-509. doi: 10.1038/emboj.2010.342. Epub 2010 Dec 21. PubMed PMID: 21179004; PubMed Central PMCID: PMC3034015.


Diede SJ, Guenthoer J, Geng LN, Mahoney SE, Marotta M, Olson JM, Tanaka H, Tapscott SJ. DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):234-9. doi: 10.1073/pnas.0907606106. Epub 2009 Dec 4. PubMed PMID: 19966297; PubMed Central PMCID: PMC2806770.

Chi Y, Clurman BE. Mass spectrometry-based identification of protein kinase substrates utilizing engineered kinases and thiophosphate labeling. Curr Protoc Chem Biol. 2010 Nov 1;2(4). pii: ch100151. PubMed PMID: 21743840; PubMed Central PMCID: PMC3131159.

Alsallaq RA, Schiffer JT, Longini IM Jr, Wald A, Corey L, Abu-Raddad LJ. Population level impact of an imperfect prophylactic vaccine for herpes simplex virus-2. Sex Transm Dis. 2010 May;37(5):290-7. doi: 10.1097/OLQ.0b013e3181d3d023. PubMed PMID: 20351622; PubMed Central PMCID: PMC2860045.

Abu-Raddad LJ, Schiffer JT, Ashley R, Mumtaz G, Alsallaq RA, Akala FA, Semini I, Riedner G, Wilson D. HSV-2 serology can be predictive of HIV epidemic potential and hidden sexual risk behavior in the Middle East and North Africa. Epidemics. 2010 Dec;2(4):173-82. doi: 10.1016/j.epidem.2010.08.003. Epub 2010 Sep 15. Review. PubMed PMID: 21352788; PubMed Central PMCID: PMC3722433.

Norquist BM, Garcia RL, Allison KH, Jokinen CH, Kernochan LE, Pizzi CC, Barrow BJ, Goff BA, Swisher EM. The molecular pathogenesis of hereditary ovarian carcinoma: alterations in the tubal epithelium of women with BRCA1 and BRCA2 mutations. Cancer. 2010 Nov 15;116(22):5261-71. doi: 10.1002/cncr.25439. PubMed PMID: 20665887; PubMed Central PMCID: PMC2975783.

Schiffer JT, Abu-Raddad L, Mark KE, Zhu J, Selke S, Koelle DM, Wald A, Corey L. Mucosal host immune response predicts the severity and duration of herpes simplex virus-2 genital tract shedding episodes. Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18973-8. doi: 10.1073/pnas.1006614107. Epub 2010 Oct 18. PubMed PMID: 20956313; PubMed Central PMCID: PMC2973882.

Lemos BD, Storer BE, Iyer JG, Phillips JL, Bichakjian CK, Fang LC, Johnson TM, Liegeois-Kwon NJ, Otley CC, Paulson KG, Ross MI, Yu SS, Zeitouni NC, Byrd DR, Sondak VK, Gershenwald JE, Sober AJ, Nghiem P. Pathologic nodal evaluation improves prognostic accuracy in Merkel cell carcinoma: analysis of 5823 cases as the basis of the first consensus staging system. J Am Acad Dermatol. 2010 Nov;63(5):751-61. doi: 10.1016/j.jaad.2010.02.056. Epub 2010 Jun 19. PubMed PMID: 20646783; PubMed Central PMCID: PMC2956767.

Paulson KG, Carter JJ, Johnson LG, Cahill KW, Iyer JG, Schrama D, Becker JC, Madeleine MM, Nghiem P, Galloway DA. Antibodies to merkel cell polyomavirus T antigen oncoproteins reflect tumor burden in merkel cell carcinoma patients. Cancer Res. 2010 Nov 1;70(21):8388-97. doi: 10.1158/0008-5472.CAN-10-2128. Epub 2010 Oct 19. PubMed PMID: 20959478; PubMed Central PMCID: PMC2970647.

Mao FJ, Sidorova JM, Lauper JM, Emond MJ, Monnat RJ. The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage. Cancer Res. 2010 Aug 15;70(16):6548-55. doi: 10.1158/0008-5472.CAN-10-0475. Epub 2010 Jul 27. PubMed PMID: 20663905; PubMed Central PMCID: PMC2941797.

Mecham BH, Nelson PS, Storey JD. Supervised normalization of microarrays. Bioinformatics. 2010 May 15;26(10):1308-15. doi: 10.1093/bioinformatics/btq118. Epub 2010 Mar 31. PubMed PMID: 20363728; PubMed Central PMCID: PMC2865860.

Herbig E, Warfield L, Fish L, Fishburn J, Knutson BA, Moorefield B, Pacheco D, Hahn S. Mechanism of Mediator recruitment by tandem Gcn4 activation domains and three Gal11 activator-binding domains. Mol Cell Biol. 2010 May;30(10):2376-90. doi: 10.1128/MCB.01046-09. Epub 2010 Mar 22. PubMed PMID: 20308326; PubMed Central PMCID: PMC2863704.

Bendoraite A, Knouf EC, Garg KS, Parkin RK, Kroh EM, O'Briant KC, Ventura AP, Godwin AK, Karlan BY, Drescher CW, Urban N, Knudsen BS, Tewari M. Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition. Gynecol Oncol. 2010 Jan;116(1):117-25. doi: 10.1016/j.ygyno.2009.08.009. Epub 2009 Oct 24. PubMed PMID: 19854497; PubMed Central PMCID: PMC2867670.

Metzger MJ, Holguin CJ, Mendoza R, Miller AD. The prostate cancer-associated human retrovirus XMRV lacks direct transforming activity but can induce low rates of transformation in cultured cells. J Virol. 2010 Feb;84(4):1874-80. doi: 10.1128/JVI.01941-09. Epub 2009 Dec 9. PubMed PMID: 20007266; PubMed Central PMCID: PMC2812358.

O'Hear C, Foote J. Antibody buffering of systemically administered lysozyme. Eur J Haematol. 2010 Mar;84(3):252-8. doi: 10.1111/j.1600-0609.2009.01383.x. Epub 2009 Nov 17. PubMed PMID: 19922461.


Schiffer JT, Abu-Raddad L, Mark KE, Zhu J, Selke S, Magaret A, Wald A, Corey L. Frequent release of low amounts of herpes simplex virus from neurons: results of a mathematical model. Sci Transl Med. 2009 Nov 18;1(7):7ra16. doi: 10.1126/scitranslmed.3000193. PubMed PMID: 20161655; PubMed Central PMCID: PMC2818652.

Carter JJ, Paulson KG, Wipf GC, Miranda D, Madeleine MM, Johnson LG, Lemos BD, Lee S, Warcola AH, Iyer JG, Nghiem P, Galloway DA. Association of Merkel cell polyomavirus-specific antibodies with Merkel cell carcinoma. J Natl Cancer Inst. 2009 Nov 4;101(21):1510-22. doi: 10.1093/jnci/djp332. Epub 2009 Sep 23. PubMed PMID: 19776382; PubMed Central PMCID: PMC2773184.

Schiffer JT, Corey L. New concepts in understanding genital herpes. Curr Infect Dis Rep. 2009 Nov;11(6):457-64. PubMed PMID: 19857385; PubMed Central PMCID: PMC2804398.

Paulson KG, Lemos BD, Feng B, Jaimes N, Peñas PF, Bi X, Maher E, Cohen L, Leonard JH, Granter SR, Chin L, Nghiem P. Array-CGH reveals recurrent genomic changes in Merkel cell carcinoma including amplification of L-Myc. J Invest Dermatol. 2009 Jun;129(6):1547-55. doi: 10.1038/jid.2008.365. Epub 2008 Nov 20. PubMed PMID: 19020549; PubMed Central PMCID: PMC2830552.

Paulson TG, Maley CC, Li X, Li H, Sanchez CA, Chao DL, Odze RD, Vaughan TL, Blount PL, Reid BJ. Chromosomal instability and copy number alterations in Barrett's esophagus and esophageal adenocarcinoma. Clin Cancer Res. 2009 May 15;15(10):3305-14. doi: 10.1158/1078-0432.CCR-08-2494. Epub 2009 May 5. PubMed PMID: 19417022; PubMed Central PMCID: PMC2684570.

Rajapakse I, Perlman MD, Scalzo D, Kooperberg C, Groudine M, Kosak ST. The emergence of lineage-specific chromosomal topologies from coordinate gene regulation. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6679-84. doi: 10.1073/pnas.0900986106. Epub 2009 Mar 10. PubMed PMID: 19276122; PubMed Central PMCID: PMC2654024.

Li H, Pellenz S, Ulge U, Stoddard BL, Monnat RJ Jr. Generation of single-chain LAGLIDADG homing endonucleases from native homodimeric precursor proteins. Nucleic Acids Res. 2009 Apr;37(5):1650-62. doi: 10.1093/nar/gkp004. Epub 2009 Jan 19. PubMed PMID: 19153140; PubMed Central PMCID: PMC2655683.

Bluemn EG, Paulson KG, Higgins EE, Sun Y, Nghiem P, Nelson PS. Merkel cell polyomavirus is not detected in prostate cancers, surrounding stroma, or benign prostate controls. J Clin Virol. 2009 Feb;44(2):164-6. doi: 10.1016/j.jcv.2008.11.008. Epub 2009 Jan 6. PubMed PMID: 19129009; PubMed Central PMCID: PMC2676318.

Pearce CL, Near AM, Van Den Berg DJ, Ramus SJ, Gentry-Maharaj A, Menon U, Gayther SA, Anderson AR, Edlund CK, Wu AH, Chen X, Beesley J, Webb PM, Holt SK, Chen C, Doherty JA, Rossing MA, Whittemore AS, McGuire V, DiCioccio RA, Goodman MT, Lurie G, Carney ME, Wilkens LR, Ness RB, Moysich KB, Edwards R, Jennison E, Kjaer SK, Hogdall E, Hogdall CK, Goode EL, Sellers TA, Vierkant RA, Cunningham JM, Schildkraut JM, Berchuck A, Moorman PG, Iversen ES, Cramer DW, Terry KL, Vitonis AF, Titus-Ernstoff L, Song H, Pharoah PD, Spurdle AB, Anton-Culver H, Ziogas A, Brewster W, Galitovskiy V, Chenevix-Trench G; Australian Cancer Study.; Australian Ovarian Cancer Study Group.. Validating genetic risk associations for ovarian cancer through the international Ovarian Cancer Association Consortium. Br J Cancer. 2009 Jan 27;100(2):412-20. doi: 10.1038/sj.bjc.6604820. Epub 2009 Jan 6. Erratum in: Br J Cancer. 2009 Nov 17;101(10):1805. Cunningham, J C [corrected to Cunningham, J M]. PubMed PMID: 19127255; PubMed Central PMCID: PMC2634713.

Garneski KM, Warcola AH, Feng Q, Kiviat NB, Leonard JH, Nghiem P. Merkel cell polyomavirus is more frequently present in North American than Australian Merkel cell carcinoma tumors. J Invest Dermatol. 2009 Jan;129(1):246-8. doi: 10.1038/jid.2008.229. Epub 2008 Jul 24. PubMed PMID: 18650846; PubMed Central PMCID: PMC2605200.

Kooperberg C, Leblanc M, Dai JY, Rajapakse IStructures and Assumptions: Strategies to Harness Gene × Gene and Gene × Environment Interactions in GWAS. Stat Sci. 2009;24(4):472-488. PubMed PMID: 20640184; PubMed Central PMCID: PMC2904990.

Goh F, Irvine KM, Lovelace E, Donnelly S, Jones MK, Brion K, Hume DA, Kotze AC, Dalton JP, Ingham A, Sweet MJ. Selective induction of the Notch ligand Jagged-1 in macrophages by soluble egg antigen from Schistosoma mansoni involves ERK signalling. Immunology. 2009 Jul;127(3):326-37. doi: 10.1111/j.1365-2567.2008.02979.x. Epub 2008 Nov 14. PubMed PMID: 19019093; PubMed Central PMCID: PMC2712101.


Hayes B, Fagerlie SR, Ramakrishnan A, Baran S, Harkey M, Graf L, Bar M, Bendoraite A, Tewari M, Torok-Storb B. Derivation, characterization, and in vitro differentiation of canine embryonic stem cells. Stem Cells. 2008 Feb;26(2):465-73. Epub 2007 Dec 6. PubMed PMID: 18065395.

Rodriguez J, Muñoz M, Vives L, Frangou CG, Groudine M, Peinado MA. Bivalent domains enforce transcriptional memory of DNA methylated genes in cancer cells. Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19809-14. doi: 10.1073/pnas.0810133105. Epub 2008 Dec 5. PubMed PMID: 19060200; PubMed Central PMCID: PMC2596747.

Chao DL, Sanchez CA, Galipeau PC, Blount PL, Paulson TG, Cowan DS, Ayub K, Odze RD, Rabinovitch PS, Reid BJ. Cell proliferation, cell cycle abnormalities, and cancer outcome in patients with Barrett's esophagus: a long-term prospective study. Clin Cancer Res. 2008 Nov 1;14(21):6988-95. doi: 10.1158/1078-0432.CCR-07-5063. PubMed PMID: 18980994; PubMed Central PMCID: PMC2587072.

Bar M, Wyman SK, Fritz BR, Qi J, Garg KS, Parkin RK, Kroh EM, Bendoraite A, Mitchell PS, Nelson AM, Ruzzo WL, Ware C, Radich JP, Gentleman R, Ruohola-Baker H, Tewari M. MicroRNA discovery and profiling in human embryonic stem cells by deep sequencing of small RNA libraries. Stem Cells. 2008 Oct;26(10):2496-505. doi: 10.1634/stemcells.2008-0356. Epub 2008 Jun 26. PubMed PMID: 18583537; PubMed Central PMCID: PMC2847579.

Chao DL, Eck JT, Brash DE, Maley CC, Luebeck EG. Preneoplastic lesion growth driven by the death of adjacent normal stem cells. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15034-9. doi: 10.1073/pnas.0802211105. Epub 2008 Sep 24. PubMed PMID: 18815380; PubMed Central PMCID: PMC2567488.

Rajapakse I, Muir L, Martin P. Hardy's "Small" Discovery Remembered. Not Am Math Soc. 2008 Mar;55(3):384-386. PubMed PMID: 22228908; PubMed Central PMCID: PMC3252052.

Garneski KM, DeCaprio JA, Nghiem P. Does a new polyomavirus contribute to Merkel cell carcinoma? Genome Biol. 2008;9(6):228. doi: 10.1186/gb-2008-9-6-228. Epub 2008 Jun 17. Review. PubMed PMID: 18598371; PubMed Central PMCID: PMC2481414.

Sycuro LK, Xi LF, Hughes JP, Feng Q, Winer RL, Lee SK, O'Reilly S, Kiviat NB, Koutsky LA. Persistence of genital human papillomavirus infection in a long-term follow-up study of female university students. J Infect Dis. 2008 Oct 1; 198(7):971-8. doi: 10.1086/591625. PubMed PMID: 18694334.