Featured Researchers

Fred Hutch scientists are among the world’s most innovative and creative researchers. They work in a setting that stresses the scientific freedom needed to achieve research breakthroughs. Read our profiles of selected researchers below to learn more about their unique work.

For more information, view the complete list of Hutch faculty members and visit the online portal for labs and research groups.

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Deputy Director, Fred Hutch
When Appelbaum was a medical student, he happened upon an early write-up of bone-marrow transplantation by Dr. E. Donnall Thomas, who later won a Nobel Prize for the pioneering blood-cancer treatment. Little did he know that one day he'd have Thomas' job at the Fred Hutch.
Geneticist and cell biologist
Biggins's breakthrough discoveries about how cells divide could lead to drugs that stop cancer cells from propagating.
Evolutionary and computational biologist
Bloom's research focuses on the evolution of viruses and on halting their drug-resistance.
Psychologist and smoking-cessation expert
By combining cutting-edge psychology and technology, Bricker is working to help millions of people adopt healthier habits that reduce their cancer risk.
Neurobiologist
Through years of intensive research, Buck became the first to identify a family of genes that control the olfactory system, a complex network that governs our sense of smell.
Co-Director, UCI/Hutchinson Center Cancer Alliance
Early in his career, Casper developed a staggering vision. He knew that more than 20 percent of cancer cases are triggered by infectious disease. And he believed that these cancers could be prevented or eliminated in a relatively short amount of time.
Director, Cancer Immunotherapy Trials Network
Just as the Fred Hutch's founders showed the world that blood cancers could be conquered, Cheever is working to create one of the nation's leading programs devoted to developing breakthrough treatments for breast, prostate, colorectal and other solid tumor cancers.
Oncologist and cancer biologist
Dr. Bruce Clurman likes to take the unexpected path. This includes his approach to devising cancer therapies. Clurman studies molecular pathways that drive cells to multiply. Molecular changes in cancer cells can accelerate tumor growth by releasing the brakes that keep normal cells in check. Rather than trying an obvious fix, like a drug-based “emergency brake” for cancer cells, Clurman is trying the opposite tack: designing therapies that encourage cancerous cells to accelerate toward a deadly crash.
Director of the Basic Sciences Division
Cooper focuses on advancing our fundamental knowledge of biology, with the goal of finding building blocks that help us understand and defeat cancer.
Virologist and Fred Hutch president and director emeritus
As a scientist, Dr. Larry Corey has led some of the most significant advances in medicine in the last 30 years: the development of safe and effective antivirals for herpes viruses, HIV, and hepatitis infections.
Cord blood transplant program director
By harnessing the healing power of umbilical cord blood, Delaney is on the forefront of developing a treatment that may prove to be a landmark breakthrough for deperately ill leukemia patients.
Biomedical Informatics Lead
Paul Fearn is the leader of the Hutchinson Integrated Data Repository and Archive (HIDRA) project at Fred Hutchinson Cancer Research Center and the Cancer Consortium.
Oncologist and clinical researcher
By studying how cells exchanged between fetus and mother connect to cancer, Gadi's research could open a door to improved cancer detection and treatment.
Head of Cancer Biology Program
Galloway's work includes breakthrough contributions to a vaccine that prevents the human papillomavirus (HPV) and averts cervical cancer.
Bioengineer and cancer researcher
A “whimsical” decision to study bioengineering started Dr. Cyrus Ghajar on a path that has led him to a new frontier in cancer research — one that could eventually lead to new methods for preventing cancer’s spread
Cell biologist
By turning to tiny yeast cells for clues, Gottschling is trying to get a better grasp on a problem that has long vexed biologists: the relationship between cancer and aging.
Cancer geneticist
Ask Grady about the link between medical research and patient treatment and he’ll tell you about the new drug therapy that saved his mother’s life.
Head of immunology
Greenberg is a world expert in discovering how rare disease-fighting cells, called T-cells, can be manipulated to treat a range of cancers—and with milder side effects than traditional therapies.
Acting president and director of Fred Hutch
Groudine says he's "not at all a top down kind of leader—I give people responsibility and turn them loose." Meanwhile, his own research as an award-winning molecular and cellular biologist has earned him international renown.
Geneticist and inventor
Renowned for his genetic research, Henikoff has developed widely used computer programs and a wealth of other research tools that have led to breakthroughs in many areas of basic science.
Oncologist and vaccine researcher
Higano is a pioneer in testing therapeutic vaccines against prostate cancer—part of a growing field of cancer research called immunotherapy, which harnesses the natural power of the immune system to fight disease.
Oncologist and pancreas cancer researcher
Hingorani's work has yielded some of the most significant advances in decades related to early detection and treatment of pancreas cancer, a disease that is almost uniformly a death sentence by the time it is detected.
Director of Human Biology Division
Holland is a physician and a scientist, a common combination in the world of medical research. Less common is the demanding combination he chose—neurosurgery and molecular biology.
Molecular and cell biologist and oncologist
Hsieh plumbs an under-examined area of cancer cell biology — control of protein synthesis — to identify new therapies for difficult-to-treat cancers.
Cancer researcher
Kemp studies both the environmental and genetic factors that lead to cancer, with an emphasis on inquiries that have a significant potential for improving patient care.
Oncologist, stem cell and gene therapy researcher
Kiem investigates how stem cells can be extracted, manipulated at a genetic level and delivered back to sick patients to treat a range of diseases, from infections like HIV to aggressive cancers.
Li is identifying important connections between breast cancer and factors such as medications, alcohol and obesity.
Transplant physician-scientist
Inspired by the memory of a boy whose life was taken too soon, Lee’s research helps patients undergoing potentially lifesaving, but risky, transplants of blood-forming stem cells.
Virus researcher
Linial is a leader in researching foamy viruses, a type of animal virus that could jump to humans and affect their health.
Oncologist, health economist and HICOR co-director
While many researchers at Fred Hutchinson Cancer Research Center are trying to find cures for cancer, Dr. Gary Lyman has an equally daunting task: finding a cure for cancer’s skyrocketing costs and the financial toll it can take on patients and their families.
Pulmonary Researcher
Dr. David Madtes’ specialized, multidisciplinary clinic is one of only a few in the country that assesses people’s risk of lung cancer and expedites evaluations of suspicious findings, using state-of-the-art diagnostic techniques.
Evolutionary geneticist
Malik studies the evolutionary struggle between viruses and humans. Ultimately, his research may lead to new drugs to fight HIV.
Immunotherapy researcher and oncologist
Maloney has played a pivotal role in developing targeted treatments that rely on special molecules called antibodies to fight cancer, including a paradigm-changing drug for lymphoma patients.
Long-Term Follow-Up program director
A veteran leukemia researcher and oncologist, Martin is devoted to improving the lives of patients who have received bone marrow or stem cell transplants.
HIV vaccine researcher
As one of the leaders of a massive international effort to develop a preventive vaccine for HIV, McElrath has spent more than two decades at the forefront of the war on AIDS.
Head of Computational Biology Program
Martin McIntosh understands that the field of computational biology requires a wide variety of scientific approaches.
Cancer prevention researcher
McTiernan's groundbreaking studies have produced some of the first specific answers about the role of exercise and weight loss in reducing cancer risk, earning her a spot on a federal advisory committee.
Surgeon and clinical researcher
Dr. Mendez tracks subtle genetic abnormalities that may drive head and neck cancers or reveal why some tumors spread while others don’t. Using state-of-the-art techniques, he’s diving deeper than physical exams or imaging tests to uncover the molecular fingerprints of each patient’s tumor.
Oncologist and cancer researcher
Mostaghel works to improve our understanding of what makes cancer treatments successful and how best to target them to patients, with a focus on prostate cancer.
Autoimmunity researcher and rheumatologist
Nelson's pioneering work on the mother-child cell transfer that happens during pregnancy, known as microchimerism, could form the basis for new therapies for people with autoimmune diseases like rheumatoid arthritis, scleroderma and diabetes.
Prostate cancer researcher and oncologist
Nelson leads investigations that seek new, more precise ways of individualizing care for prostate cancer's varied forms.
Brain cancer researcher
Olson is focused on developing new ways to remove brain tumors, finding new treatments for tumors that have few therapy options and identifying new uses for existing drugs.
Geneticist
Employing a cutting-edge technology called RNA interference, Paddison investigates why cells behave in particular ways--work that could lead to better therapies for many diseases.
Oncologist and cancer geneticist
Paulovich's lab develops technologies aimed at rapidly screening large numbers of telltale proteins—known as "biomarkers"—for clues that may indicate the earliest stages of cancer and other diseases.
Geneticist
By examining the evolution of body type and behavior in stickleback fish, Peichel works to shed light on the genetic networks at play in other complex traits, such as cancer and other common human diseases.
Radioimmunotherapy researcher and oncologist
Some of the world's most successful treatments for lymphoma and other blood cancers have emerged from research by Press and colleagues, who pioneered the use of radioactive molecules that blast cancer with high doses of radiation while sparing healthy cells.
Leukemia Researcher
Radich’s research has led to important breakthroughs in leukemia detection and treatment since he came to Fred Hutch 25 years ago. His work involves sniffing out tiny numbers of cancer cells based on their genetic signature.
Physician, cancer researcher, and health economist
When Ramsey talks about medicine, his upturned palms often rise to form an imaginary scale. As a physician, cancer researcher and health economist, he weighs the cost and benefit of various treatments, doggedly advocating for the best patient care for the least amount of money.
Immunotherapy researcher and oncologist
Riddel is fortifying the immune system with better weapons: long-living T-cells specially engineered to seek and destroy cancer.
Biologist
Whether researching cell processes that lead to cancer or riding his bike, Roberts has a penchant for the road less traveled.
Cell biologist
Growing up in an orphanage in Hershey, Pa., Roth often heard "no" from the adults in his life. No, he couldn't run on the high-school track or cross-country teams. No, he'd never be a scientist. Now his research may one day transform emergency medicine.
Microbiologist
Salama studies Helicobacter pylori, a cancer-linked bacterium that relies on its unusual corkscrew shape to burrow into the stomach lining, sometimes triggering ulcers and gastric cancer.
Molecular immunologist
Why are some cancer cells so successful at dodging our body's natural disease-fighting powers? That's the major research question that motivates Spies and his colleagues, whose work may lead to new approaches for cancer treatment.
Director of Program in Prostate Cancer Research
The hope of cancer prevention motivates Stanford on a very personal level. Five of her close family members have fought the disease. "I look at my son," she says, "and I am inspired to do something to prevent him from getting prostate cancer like both of his grandfathers."
Structural biologist
In his laboratory at the Hutchinson Center, Dr. Barry Stoddard uses some of the most advanced technology in the world to probe the structure and function of biological molecules atom by atom.
Head of Transplantation Biology Program
Much of what scientists have learned—and are still learning—about the biology of stem-cell transplantation came from Storb's laboratory. He continues to pioneer new blood-cancer treatments after working on team led by Dr. E. Donnall Thomas, the father of bone marrow transplantation.
Biophysicist
With his expertise in determining molecules’ structures and functions, Strong collaborates with clinicians to design and create new diagnostics and therapeutics.
Cancer biologist
Taniguchi delves into a natural process called DNA repair to shed light on a phenomenon that has long vexed oncologists: why anti-cancer drugs often decline in effectiveness over time.
Transplant biologist and mentor
Torok-Storb overcame the odds to become a scientist who has helped improve patients’ outcomes following transplants of blood-forming stem cells. Now she’s inspiring the next generation of researchers to make their own discoveries.
Turtle is among many scientists around the world who are harnessing the body's immune system to fight cancer.
Immunotherapy researcher and oncologist
Through refining a technique called adoptive T-cell therapy, Warren is working to develop treatments that use the body's immune system to attack kidney and colon cancers more precisely while sparing healthy organs.