Dr. Mark Groudine is executive vice president and deputy director of Fred Hutch and a member of the Center's Basic Sciences Division.
Research in Groudine's laboratory focuses on the relationships between gene expression, chromatin structure and the organization of the cell nucleus during cellular differentiation and the transformation of normal cells to cancer cells.
His work includes the development of techniques for studying gene regulation as well as the discovery of elements that regulate the expression of large regions of chromosomes.
Groudine also holds appointments at University of Washington, where he is a professor and attending physician in the Department of Radiation Oncology and an adjunct professor in the Department of Pathology. He also serves on the board of directors of Seattle Cancer Care Alliance.
Groudine received his M.D. and Ph.D. degrees in 1975 and 1976 from the University of Pennsylvania. After postdoctoral training at Princeton University and residency in radiation oncology at UW, he joined the Hutchinson Center in 1979. He served as director of the Hutchinson Center's Basic Sciences Division from 1995 to 2004. He has served on many committees involved in the establishment of national cancer policy, including the Board of Scientific Counselors for the Division of Cancer Treatment at the National Cancer Institute.
Groudine was awarded the Allison Eberlein Fund Award for major contributions in the field of hematology/oncology and is a fellow in the American Association for the Advancement of Science. He was elected to the National Academy of Sciences in 2001, to the Institute of Medicine of the National Academies in 2003 and to the American Academy of Arts and Sciences in 2006.